NCT05228782 (SIL) is a NA clinical trial of HOW R U? Intervention in Social Isolation, sponsored by Mount Sinai Hospital, Canada.

Who is sponsoring NCT05228782?

NCT05228782 is sponsored by Mount Sinai Hospital, Canada.

What drugs are being tested in NCT05228782?

Interventions in NCT05228782: HOW R U? Intervention.

What condition does NCT05228782 study?

NCT05228782 studies Social Isolation, Loneliness, Geriatric.

Is NCT05228782 still recruiting?

NCT05228782 is currently status unknown. Last updated 8 February 2022.

Last reviewed 2022-02-08 · How we verify

NCT05228782: SIL

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

COVID-19 and Social Isolation and Loneliness Trial

Status unknown NA Last updated 8 February 2022

What this trial tests

NA trial testing HOW R U? Intervention in Social Isolation in 141 participants. Status unknown.

Timeline

1 November 2021

Primary endpoint
1 November 2022

3 November 2023

Quick facts

Lead sponsor	Mount Sinai Hospital, Canada
Phase	NA
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	supportive care
Enrollment	141
Start date	1 November 2021
Primary completion	1 November 2022
Estimated completion	3 November 2023
Sites	1 location across Canada

Drugs / interventions tested

HOW R U? Intervention

Conditions studied

Social Isolation — all drugs for Social Isolation →
Loneliness — all drugs for Loneliness →
Geriatric — all drugs for Geriatric →

Sponsor

Mount Sinai Hospital, Canada

Who can join

70 and older, any sex, with Social Isolation or Loneliness. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Social isolation and loneliness worsen older peoples' quality of life, risk of dementia, and contributes to 45,000 deaths/year in Canada - as much as smoking. Isolated people use the health care system more often, but have worse outcomes. Effective, inexpensive interventions exist but unfortunately they have not been implemented in Canada. We partnered with the Australian developer of HOW R U?, an effective and feasible intervention that uses specially trained, older, hospital volunteers to provide peer support to combat isolation and loneliness in isolated older peers. Little is known about older people's preferences for virtual care (telephone vs. video) nor their relative effectiveness. Thus we will compare two ways of delivering HOW R U: telephone support and a tested, secure user-friendly video conferencing app, aTouch Away® to a common control arm. We also partnered with Emergency Medicine, Family Medicine, Geriatrics and Psychiatry to identify people who will benefit from peer support; and with Volunteer Services to recruit volunteers.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Impact of a peer-support programme to improve loneliness and social isolation due to COVID-19: does adding a secure, user friendly video-conference solution work better than telephone support alone? Protocol for a three-arm randomised clinical trial.
Lee JS, Rose L, Borgundvaag B, McLeod SL, et al · · 2024 · cited 1× · PMID 38199634 · DOI 10.1136/bmjopen-2021-056839

Verify or expand the search:

Other recruiting trials for Social Isolation

Currently open trials in the same condition.

NCT06803329 — Qnnections: Refinement and Pilot Trial of a Suicide Prevention Intervention to Increase Social Connection · NA · recruiting
NCT07107906 — Evaluating and Implementing The CONNECT Program - a Group-Based Telehealth Intervention to Reduce Social Isolation, Lone · NA · recruiting
NCT07089914 — Health Surveillance at University of Applied Science Hamburg (HAW) · active not recruiting
NCT06510439 — Need to be Needed (N2BN) Intervention · NA · recruiting
NCT06467214 — Increasing Veterans' Social Engagement and Connectedness · NA · recruiting

Other Mount Sinai Hospital, Canada trials

Trials by the same sponsor.

NCT07272460 — Time Restricted-EAting for Type 2 Diabetes and MEtabolic Health: the TEA TIME Trial · NA · recruiting
NCT07046572 — Methoxyflurane for IUD Insertion and Endometrial Biopsy · NA · recruiting
NCT06504277 — Low Versus Standard Pressure Pneumoperitoneum on Shoulder Tip Pain · NA · recruiting
NCT06546254 — 1% Lidocaine Paracervical Block for Endometrial Biopsy · NA · completed
NCT06733701 — The Use of Virtual Reality Technology During Oocyte Retrieval for in Vitro Fertilization · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05228782 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Mount Sinai Hospital, Canada
Last refreshed: 8 February 2022

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05228782.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing