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NCT05226962
The Effects of Acute Ketone Monoester Supplementation on 20-Minute Time-Trial Performance in Trained Cyclists
NA trial testing Ketone monoester in Exercise in 25 participants. Completed in 1 October 2022.
1 September 2022
Quick facts
| Lead sponsor | McMaster University |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | crossover |
| Masking | double |
| Primary purpose | basic science |
| Enrollment | 25 |
| Start date | 15 February 2022 |
| Primary completion | 1 September 2022 |
| Estimated completion | 1 October 2022 |
| Sites | 1 location across Canada |
Drugs / interventions tested
- Ketone monoester
- Placebo
Conditions studied
Sponsor
McMaster University
Who can join
Adults 18 to 60, any sex, with Exercise or Ketosis. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Diet can alter blood ketone levels and this in turn may affect exercise capacity. This study will determine if the acute ingestion of a ketone supplement alters cycling time trial performance. Participants will perform two trials in a randomized order. Each trial will involve a 20-minute bout of cycling on a stationary ergometer. Participants will ingest either a ketone supplement or a taste-matched placebo drink prior to exercise. Blood samples will be obtained to assess selected metabolic responses. This study will provide information regarding the effect of ketone supplementation on exercise responses.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT05226962
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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- NCT05665855 — The Effects of Acute Ketone Monoester Supplementation on Exercise Efficiency and the Influence of Dose and Intensity · NA · completed
- NCT05294939 — Efficacy of Acute Intake of Ketones on Performance in Professional Road Cyclists · NA · completed
- NCT05161676 — Metabolic Effects of Chronic Ketosis (KETO-CHF Metabolic) · Phase 2 · completed
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05226962 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by McMaster University
- Last refreshed: 7 November 2022
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05226962.
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