Last reviewed · How we verify
NCT05220345: DiscoveryIII
Synergistic Effect of G-Eye Balloon for Behind the Folds Visualization With CADe (Discovery System) on Adenoma Detection Rate.
NA trial testing colonoscopy assisted by both balloon-Behind The Folds visualizing and Computer assisted detection (CADe) in Colorectal Polyp in 196 participants. Completed in 26 September 2024.
26 August 2024
Quick facts
| Lead sponsor | Radboud University Medical Center |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | diagnostic |
| Enrollment | 196 |
| Start date | 12 May 2022 |
| Primary completion | 26 August 2024 |
| Estimated completion | 26 September 2024 |
| Sites | 1 location across Netherlands |
Drugs / interventions tested
- colonoscopy assisted by both balloon-Behind The Folds visualizing and Computer assisted detection (CADe)
Conditions studied
- Colorectal Polyp — all drugs for Colorectal Polyp →
- Colonoscopy — all drugs for Colonoscopy →
- Artificial Intelligence — all drugs for Artificial Intelligence →
- Adenoma — all drugs for Adenoma →
Sponsor
Radboud University Medical Center
Who can join
18 and older, any sex, with Colorectal Polyp or Colonoscopy. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Colonoscopy is the gold standard for colorectal screening. The diagnostic accuracy of colonoscopy highly depends on the quality of inspection of the colon during the procedure. To increase detection new polyp detection systems based on artificial intelligence (AI) have been developed. However, these systems still depend on the ability of the endoscopist to adequately visualize the complete colonic mucosa, especially to detect smaller and more subtle lesions, or lesions hidden behind folds in the colon. With this study we want to combine a device to flatten the folds in the colon combined with an artificial intelligence system to further improve the detection rate of lesions during colonoscopy.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Effect of Combination of a Mucosal Exposure Device and Computer-Aided Detection in Diagnostic, Screening, and Surveillance Colonoscopy: An International, Multicenter Study.
Maas MHJ, van Riswijk MLM, Rath T, Cesaro P, et al · · 2026 · PMID 41363762 · DOI 10.14309/ctg.0000000000000963
Verify or expand the search:
- PubMed search for NCT05220345
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Colorectal Polyp
Currently open trials in the same condition.
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- NCT06502704 — Bile Acids and Microbiome in Early Colorectal Carcinogenesis · recruiting
- NCT06447012 — Artificial Intelligence Development for Colorectal Polyp Diagnosis · recruiting
Other Radboud University Medical Center trials
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05220345 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Radboud University Medical Center
- Last refreshed: 15 August 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05220345.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing