NCT05219708

High Calorie High Protein Nutrition Supplementation in Advanced Heart Failure

Completed NA Last updated 6 December 2024

What this trial tests

NA trial testing Calorie protein supplement in Heart Failure in 33 participants. Completed in 30 June 2024.

Timeline

5 April 2022

Primary endpoint
2 April 2024

30 June 2024

Quick facts

Lead sponsor	Columbia University
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	double
Primary purpose	treatment
Enrollment	33
Start date	5 April 2022
Primary completion	2 April 2024
Estimated completion	30 June 2024
Sites	1 location across United States

Drugs / interventions tested

• Calorie protein supplement
• Control

Conditions studied

• Heart Failure — all drugs for Heart Failure →

Sponsor

Columbia University

Who can join

18 and older, any sex, with Heart Failure. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

In this study, the investigators will determine the impact of a high calorie and high protein nutrition supplementation strategy on quality of life in participants with advanced heart failure. The investigators hypothesize that participants with advanced heart failure who receive the high calorie high protein nutrition supplementation strategy will experience an improvement in quality of life compared to those patients that receive usual care.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

1. The Association Between Preoperative Pectoralis Muscle Quantity and Outcomes After Cardiac Transplantation.
   Driggin E, Chung A, Harris E, Bordon A, et al · · 2024 · cited 9× · PMID 38616005 · DOI 10.1016/j.cardfail.2024.03.012
2. When the Heart, Kidneys, and Body Waste Away: A Review of Cachexia in Cardiorenal Syndrome.
   Sarnaik KS, Mirzai S. · · 2025 · cited 1× · PMID 40875155 · DOI 10.1007/s11897-025-00711-2