Who is sponsoring NCT05216744?

NCT05216744 is sponsored by Haiphong University of Medicine and Pharmacy.

What drugs are being tested in NCT05216744?

Interventions in NCT05216744: Ceftriaxone 1000mg + doxycycline 100 mg, Cefixime 800mg + doxycycline 100 mg.

What condition does NCT05216744 study?

NCT05216744 studies Neisseria Gonorrhoeae Infection, Chlamydia Trachomatis Infection.

Is NCT05216744 still recruiting?

NCT05216744 is currently completed. Last updated 17 March 2022.

Last reviewed 2022-03-17 · How we verify

NCT05216744

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Comparison of Efficacy of Two Combination Regimens for the Neisseria Gonorrhoeae and Chlamydia Coinfection

Completed Phase 2 Last updated 17 March 2022

What this trial tests

Phase 2 trial testing Ceftriaxone 1000mg + doxycycline 100 mg in Neisseria Gonorrhoeae Infection in 125 participants. Completed in 20 February 2022.

Timeline

15 July 2021

Primary endpoint
15 February 2022

20 February 2022

Quick facts

Lead sponsor	Haiphong University of Medicine and Pharmacy
Phase	Phase 2
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	treatment
Enrollment	125
Start date	15 July 2021
Primary completion	15 February 2022
Estimated completion	20 February 2022
Sites	1 location across Vietnam

Drugs / interventions tested

Ceftriaxone 1000mg + doxycycline 100 mg — full drug profile →
Cefixime 800mg + doxycycline 100 mg — full drug profile →

Conditions studied

Neisseria Gonorrhoeae Infection — all drugs for Neisseria Gonorrhoeae Infection →
Chlamydia Trachomatis Infection — all drugs for Chlamydia Trachomatis Infection →

Sponsor

Haiphong University of Medicine and Pharmacy

Who can join

18 and older, any sex, with Neisseria Gonorrhoeae Infection or Chlamydia Trachomatis Infection. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The frequency of Chlamydia trachomatis and Neisseria gonorrhoeae coinfection can vary depending on their individual incidence and prevalence rates.Single-agent therapy with ceftriaxone is the preferred regimen for treatment of gonococcal infections. If an injectable cephalosporin is not available, cefixime is the only oral cephalosporin that can be used for gonococcal therapy. Doxycycline was recommended for presumptive treatment of chlamydia in nonpregnant individuals with gonococcal infection. The study is conducted to evaluate the effectiveness of two regimens in combination with doxycycline with cefixime or ceftriaxone.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Randomized controlled trial of the relative efficacy of high-dose intravenous ceftriaxone and oral cefixime combined with doxycycline for the treatment of Chlamydia trachomatis and Neisseria gonorrhoeae co-infection.
Nguyen PTT, Pham HV, Van DH, Pham LV, et al · · 2022 · cited 5× · PMID 35810277 · DOI 10.1186/s12879-022-07595-w

Verify or expand the search:

Other recruiting trials for Neisseria Gonorrhoeae Infection

Currently open trials in the same condition.

NCT05286931 — SpeeDx Ciprofloxacin gyrA Assay for N. Gonorrhoeae Gonococcal Infection · NA · recruiting

Other Haiphong University of Medicine and Pharmacy trials

Trials by the same sponsor.

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NCT07032558 — Comparison of DW-1021 and Separate Doses of Pelubi CR and Zytram CR Under Fasting Conditions · Phase 1 · recruiting
NCT07060209 — Food Effect on PK of DW-1021 (Pelubiprofen 45 mg / Tramadol 45.9 mg) in Healthy Adults · Phase 1 · recruiting
NCT07148583 — BioAmicus Complete for Functional Gastrointestinal Symptoms in Infants Aged 0 to 24 Months · NA · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05216744 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Haiphong University of Medicine and Pharmacy
Last refreshed: 17 March 2022

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05216744.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing