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NCT05215873
Induction of Labor in Pregnant Women With Prelabor Rupture of Membranes - Oxytocin or Misoprostol
Phase 4 trial testing Misoprostol in Prelabor Rupture of Membranes in 200 participants. Completed in 16 May 2022.
15 January 2022
Quick facts
| Lead sponsor | Ain Shams Maternity Hospital |
|---|---|
| Phase | Phase 4 |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 200 |
| Start date | 1 February 2021 |
| Primary completion | 15 January 2022 |
| Estimated completion | 16 May 2022 |
| Sites | 1 location across Egypt |
Drugs / interventions tested
- Misoprostol (Misoprostol) — full drug profile →
- Syntocinon — full drug profile →
Conditions studied
- Prelabor Rupture of Membranes — all drugs for Prelabor Rupture of Membranes →
Sponsor
Ain Shams Maternity Hospital
Who can join
Adults 18 to 40, female only, with Prelabor Rupture of Membranes. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The aim of study is to compare the efficacy and safety of oral misoprostol versus oxytocin in induction of labor in pregnant women with prelabor rupture of membranes at term.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Oxytocin Versus Oral Misoprostol for Induction of Labor in Pregnant Women with Term Prelabor Rupture of Membranes: a Randomized Clinical Trial.
Ahmed RHM, Sweed MSE, El-Bishry GA, Hassan RK. · · 2023 · cited 7× · PMID 37442883 · DOI 10.1007/s43032-023-01290-0
Verify or expand the search:
- PubMed search for NCT05215873
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Misoprostol
Trials testing the same drug.
- NCT07353281 — Carbetocin vs Misoprostol for Postpartum Hemorrhage Prevention · NA · not yet recruiting
- NCT06669533 — Use Misoprostol to Optimize Prevention of Cervical Cancer · NA · recruiting
- NCT07416487 — Comparison of Outcome of Foley Catheter Versus Misoprostol for Induction of Labor · NA · completed
- NCT06765473 — Comparison Between Preoperative Vaginal and Postoperative Sublingual Misoprostol for Prevention of Postpartum Hemorrhage · Phase 3 · not yet recruiting
- NCT06452719 — Letrozole and Misoprostol for Early Pregnancy Loss Management · Phase 2 · recruiting
Other Ain Shams Maternity Hospital trials
Trials by the same sponsor.
- NCT07514078 — Evaluation of Laparoscopic Staging Versus Staging Laparotomy for Early Stage Endometrial Cancer · NA · not yet recruiting
- NCT07308977 — Practice of Assisted Vaginal Birth in Egypt · not yet recruiting
- NCT06935422 — Role of Cerebroplacental Ratio Discordance at 16-20 Weeks in Predicting Monochorionic Twin Pregnancies' Specific Complic · recruiting
- NCT06524700 — Pectopexy Autologous Vs Mesh · NA · active not recruiting
- NCT07247851 — Title of the Protocol: Combined Use of Vaginal Clindamycin Cream and Oral Metronidazole Versus Oral Metronidazole · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05215873 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Ain Shams Maternity Hospital
- Last refreshed: 23 June 2022
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05215873.
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