Limerick - Liver Magnetic Resonance Imaging Before Treatment for Rectal Cancer. A Randomised Controlled Trial.

NCT05215535 NA RECRUITING

This multicentre randomized controlled trial aims to investigate whether an abbreviated MRI is comparable to a combined single venous phase CT with an additional 3 min equilibrium phase of the liver, in the pretreatment radiological workup in patients with rectal cancer.

Details

Lead sponsor	Vastra Gotaland Region
Phase	NA
Status	RECRUITING
Enrolment	400
Start date	2022-04-12
Completion	2029-12

Conditions

• Rectal Cancer

Interventions

• Abbreviated MRI of the liver/abdomen
• Combined single venous and 3 min equilibrium phase CT of the abdomen/liver

Primary outcomes

• Need for supplementary radiologic liver examination — 3 months
  Number of patients in need for supplementary radiologic liver examination/s before treatment decision, after index examination (CT or MRI) of the abdominal organs, due to inconclusive results.
• Cost effectiveness — 12 months
  Costs related to all index radiological examinations will be included. Costs will be collected from national sources such as the Swedish association of local authorities and regions (SKR - Sveriges kommuner och regioner) whenever possible and alternatively from Sahlgrenska university hospital cost-per-patient files. Possibly a more complex model will be relevant depending on outcome, where total health care costs are compared between the two radiological work-up routines. Such an analysis will take survival into account.

Countries

Sweden