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NCT05212532

A Proof-of-Concept Study Evaluating EOM613 in COVID-19 Infected Patients With Severe Symptoms

Status unknown Phase 1 Last updated 28 January 2022
What this trial tests

Phase 1 trial testing EOM613 in COVID-19 Pneumonia in 40 participants. Status unknown.

Timeline
9 August 2021
Primary endpoint
28 February 2022
30 March 2022

Quick facts

Lead sponsorEOM Pharmaceuticals
PhasePhase 1
StatusStatus unknown
Study typeINTERVENTIONAL
Allocationnon randomized
Designparallel
Maskingnone
Primary purposetreatment
Enrollment40
Start date9 August 2021
Primary completion28 February 2022
Estimated completion30 March 2022
Sites4 locations across Brazil

Drugs / interventions tested

Conditions studied

Sponsor

EOM Pharmaceuticals — full company profile →

Who can join

Adults 18 to 84, any sex, with COVID-19 Pneumonia or COVID-19 Respiratory Infection. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The purpose of this study is to evaluate the safety, tolerability and preliminary efficacy of EOM613, a peptide nucleic acid with novel immune-modulating properties, in treating patients with severe COVID-19 infections. This proof-of-concept study is the first clinical trial of EOM613 in this patient population.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. Treatment of Human Glioblastoma U251 Cells with Sulforaphane and a Peptide Nucleic Acid (PNA) Targeting miR-15b-5p: Synergistic Effects on Induction of Apoptosis.
    Gasparello J, Papi C, Zurlo M, Gambari L, et al · · 2022 · cited 19× · PMID 35209084 · DOI 10.3390/molecules27041299

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Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05212532.

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