Last reviewed · How we verify
NCT05210595
Optimal Dosage of Ticagrelor in Korean Patients With AMI
Phase 4 trial testing Clopidogrel 75 mg in Acute Myocardial Infarction in 120 participants. Status unknown.
31 December 2022
Quick facts
| Lead sponsor | Dong-A University |
|---|---|
| Phase | Phase 4 |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 120 |
| Start date | 1 January 2022 |
| Primary completion | 31 December 2022 |
| Estimated completion | 31 December 2023 |
| Sites | 1 location across South Korea |
Drugs / interventions tested
- Clopidogrel 75 mg
- Ticagrelor 60mg — full drug profile →
- Ticagrelor 45 mg — full drug profile →
Conditions studied
- Acute Myocardial Infarction — all drugs for Acute Myocardial Infarction →
- Ticagrelor — all drugs for Ticagrelor →
Sponsor
Dong-A University
Who can join
Adults 20 to 75, any sex, with Acute Myocardial Infarction or Ticagrelor. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
East Asian patients will be required optimal dose of newer P2Y12 inhibitor (ticagrelor) to determine the safer treatment and better outcome. Whether low dose of ticagrelorI is more adequate for clinical practice in Korea is unclear. Therefore, the investigators aim to evaluate efficacy and safety of low dose of ticagrelor in Acute Myocardial Infarction (AMI) undergoing percutaneous coronary intervention(PCI).
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Antiplatelet Therapy Aims and Strategies in Asian Patients with Acute Coronary Syndrome or Stable Coronary Artery Disease.
Tam CC, Tse HF. · · 2022 · cited 6× · PMID 36556067 · DOI 10.3390/jcm11247440
Verify or expand the search:
- PubMed search for NCT05210595
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Clopidogrel 75 mg
Trials testing the same drug.
- NCT04738097 — Efficacy of Ticagrelor Plus Aspirin in Mild Non-cardioembolic Ischemic Stroke · Phase 3 · completed
- NCT03814642 — Effect of Tegoprazan on Pharmacodynamics of Clopidogrel in Healthy Male Participants · Phase 1 · completed
Other recruiting trials for Acute Myocardial Infarction
Currently open trials in the same condition.
- NCT03951467 — Using an Intervention Adapted to the Health Literacy Level to Improve Adherence to Medical Recommendations · NA · recruiting
- NCT07536802 — Adenosine Pre-Medication in Primary Percutaneous Coronary Intervention: A Randomized Control Trial · Phase 4 · recruiting
- NCT06947135 — Stellate Ganglion Morphine Infiltration on Myocardial Ischemia-Reperfusion Injury · NA · recruiting
- NCT06515730 — Treatment With Apixaban Versus Warfarin in Patients With Left Ventricular Thrombus After Acute Myocardial Infarction · Phase 4 · recruiting
- NCT07522164 — Acute Myocardial Infarction Clinical Cohort · active not recruiting
Other Dong-A University trials
Trials by the same sponsor.
- NCT04755387 — Ticagrelor De-escalation Strategy in AMI Patients · Phase 4 · recruiting
- NCT05225077 — Short-term Use of Dapagliflozin to Protect Kidney Function in CKD Patients · Phase 4 · unknown
- NCT04174456 — Combination of Olmesartan Effect on Myocardial Viability of Patients With Dilated Cardiomyopathy · NA · unknown
- NCT03570671 — Noninvasive Cardiac Imaging in Vasospastic Angina Korean Registry (NAVIGATOR) · NA · unknown
- NCT03731988 — Efficacy of Ablative Fractional Laser-assisted Photodynamic Therapy According to the Laser Density for Actinic Keratosis · Phase 4 · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05210595 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Dong-A University
- Last refreshed: 27 January 2022
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05210595.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing