Last reviewed · How we verify
NCT05204940: OPT-Neuro
Longitudinal Observational Biomarker Study
trial testing Mechanisms of Late life depression (LLD)-dementia through functional Magnetic Resonance Imaging (fMRI) in Depression in 506 participants. Completed in 31 July 2024.
31 July 2024
Quick facts
| Lead sponsor | Centre for Addiction and Mental Health |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 506 |
| Start date | 27 September 2017 |
| Primary completion | 31 July 2024 |
| Estimated completion | 31 July 2024 |
| Sites | 5 locations across Canada, United States |
Drugs / interventions tested
- Mechanisms of Late life depression (LLD)-dementia through functional Magnetic Resonance Imaging (fMRI)
- Neuropsychological Data
- Clinical Scales
Conditions studied
- Depression — all drugs for Depression →
- Dementia — all drugs for Dementia →
- Mild Cognitive Impairment — all drugs for Mild Cognitive Impairment →
Sponsor
Centre for Addiction and Mental Health — full company profile →
Who can join
60 and older, any sex, with Depression or Dementia. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The purpose of this study is to test whether treatment-resistant late life depression is associated with declines in memory and attention and brain structure and function.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT05204940
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
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Other Centre for Addiction and Mental Health trials
Trials by the same sponsor.
- NCT07211438 — Evaluating the Role of Psilocybin Monitors in Psilocybin Therapy for Treatment Resistant Depression · Phase 2 · not yet recruiting
- NCT07146633 — Efficacy of an EMDR App for PTSD and SUD · NA · recruiting
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- NCT07105449 — THC Titration of High-Potency Cannabis Concentrates · NA · not yet recruiting
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05204940 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Centre for Addiction and Mental Health
- Last refreshed: 25 November 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05204940.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing