Last reviewed · How we verify
Near InfraRed Fluorescence Imaging of Lymphatic Transport Using Indocyanine Green: Phase II Pilot
Lymphatic transport was previously examined by these investigators using Near InfraRed Indocyanine Green fluorescence imaging (NIR-ICG) of the upper extremities. They established reliable and reproducible methodologies in RA patients. The purpose of this phase 2 pilot is to study RA disease progression and effectiveness as well as the mechanism of action of clinical interventions using established NIR-ICG methodologies in previous studies.
Details
| Lead sponsor | University of Rochester |
|---|---|
| Phase | Phase 1 |
| Status | RECRUITING |
| Enrolment | 40 |
| Start date | 2021-12-30 |
| Completion | 2025-12 |
Conditions
- Rheumatoid Arthritis
Interventions
- Indocyanine green
- MultiSpectral Imaging System
Primary outcomes
- Clearance — 1 week post injection
The change in Indocyanine Green signal intensity (arbitrary units) over time is measured by observing the fluorescence using the Multispectral Imaging System. The MSImager software analyses the signal intensity. This outcome measure will be quantified for both early RA and late RA subjects.
Countries
United States