NCT05197439 is a NA clinical trial of Dexmedetomidine in Dexmedetomidine, sponsored by Beijing Tiantan Hospital.

Who is sponsoring NCT05197439?

NCT05197439 is sponsored by Beijing Tiantan Hospital.

What drugs are being tested in NCT05197439?

Interventions in NCT05197439: Dexmedetomidine, 0.9% saline.

What condition does NCT05197439 study?

NCT05197439 studies Dexmedetomidine, Postoperative Delirium, Deep Brain Stimulation.

Is NCT05197439 still recruiting?

NCT05197439 is currently status unknown. Last updated 15 June 2023.

Last reviewed 2023-06-15 · How we verify

NCT05197439

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Dexmedetomidine Prevents Postoperative Delirium After Deep Brain Stimulation in Patients With Parkinson's Disease

Status unknown NA Last updated 15 June 2023

What this trial tests

NA trial testing Dexmedetomidine in Dexmedetomidine in 192 participants. Status unknown.

Timeline

1 December 2023

Primary endpoint
30 November 2024

31 December 2024

Quick facts

Lead sponsor	Beijing Tiantan Hospital
Phase	NA
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	quadruple
Primary purpose	prevention
Enrollment	192
Start date	1 December 2023
Primary completion	30 November 2024
Estimated completion	31 December 2024
Sites	1 location across China

Drugs / interventions tested

Dexmedetomidine (dexmedetomidine) — full drug profile →
0.9% saline

Conditions studied

Dexmedetomidine — all drugs for Dexmedetomidine →
Postoperative Delirium — all drugs for Postoperative Delirium →
Deep Brain Stimulation — all drugs for Deep Brain Stimulation →

Sponsor

Beijing Tiantan Hospital

Who can join

60 and older, any sex, with Dexmedetomidine or Postoperative Delirium. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Postoperative delirium (POD) is a common complication, and the incidence of POD after deep brain stimulation(DBS) implementation ranges from 10% to 40%. Previous studies suggested that aging and existing non-motor symptom were independent risk factors for POD after supratentorial tumor resections. Therefore, patients undergoing DBS are high-risk populations for POD. A lot of trials show that dexmedetomidine might help to reduce the incidence of delirium in patients undergoing non-cardiac surgery. However, the impact of dexmedetomidine on POD for patients undergoing DBS was seldom reported. The purpose of this study was to investigate the effect of dexmedetomidine on POD in patients with Parkinson' Disease undergoing DBS.

Publications & conference data

3 peer-reviewed publications reference this trial (live from Europe PMC):

Deep Brain Stimulation for the Management of Refractory Neurological Disorders: A Comprehensive Review.
Rissardo JP, Vora NM, Tariq I, Mujtaba A, et al · · 2023 · cited 17× · PMID 38004040 · DOI 10.3390/medicina59111991
Dexmedetomidine after deep brain stimulation for prevention of delirium in elderly patients with Parkinson's disease: protocol for a single-centre, randomised, double-blind, placebo-controlled trial in China.
Yao J, Shen Z, Jin H, Ma T, et al · · 2023 · cited 2× · PMID 37433729 · DOI 10.1136/bmjopen-2022-070185
Fountain of youth-Targeting autophagy in aging.
Danics L, Abbas AA, Kis B, Pircs K. · · 2023 · cited 2× · PMID 37065462 · DOI 10.3389/fnagi.2023.1125739

Verify or expand the search:

Other trials of Dexmedetomidine

Trials testing the same drug.

NCT06824077 — Reducing Days DELirious With DEXmedetomidine as Part of an Intensive Care Unit Sleep Promotion Bundle · EARLY_PHASE1 · not yet recruiting
NCT07398066 — DEXmedetomidine for Postoperative Analgesia and Delirium Prevention After NEUROsurgery (DEX-NEURO Trial) · NA · not yet recruiting
NCT07377981 — An Exploratory Study of the Efficacy and Safety of Esketamine and Dexmedetomidine in Non-Intubated ICU Patients With Hyp · Phase 4 · not yet recruiting
NCT07306702 — Dexmedetomidine-Enhanced PCIA After Lobectomy in Nicotine-Dependent Patients · Phase 4 · withdrawn
NCT07482540 — Role of Dexmedatomidine Drug in Prevention of Atrial Fibrillations Post Mitral Valve Surgery · NA · not yet recruiting

Other recruiting trials for Dexmedetomidine

Currently open trials in the same condition.

NCT07508202 — Comparison of Post Operative Analgesia in Patients Undergoing Lower Abdominal Surgeries Receiving Ultrasound Guided Bloc · Phase 4 · recruiting
NCT07523438 — Effect of Intranasal Dexmedetomidine on the Incidence of Emergence Agitation in Children Undergoing Strabismus Surgery · NA · recruiting
NCT07343843 — Virtual Reality Versus Intravenous Dexmedetomidine on Maternal Anxiety, Stress, Hemodynamics, and Neonatal Outcomes Duri · NA · recruiting
NCT07327905 — Intravenous Lidocaine Infusion Versus Intravenous Dexmedetomidine Infusion During Sleeve Gastrectomy · NA · recruiting
NCT07276867 — Intrathecal Dexmedetomidine-Fentanyl Combination Versus Fentanyl Alone as Adjuvant to Bupivacaine in Spinal Anesthesia f · NA · recruiting

Other Beijing Tiantan Hospital trials

Trials by the same sponsor.

NCT07341854 — Dexamethasone Palmitate for Postoperative Pain · NA · not yet recruiting
NCT07527013 — Stratified Blood Pressure Management Strategy After Endovascular Treatment for Acute Ischemic Stroke · Phase 3 · not yet recruiting
NCT07520370 — Effect of Perioperative Ulinastatin on Postoperative Stroke in Patients With Brain Tumor · NA · not yet recruiting
NCT07526987 — Efficacy and Safety of Minocycline in Patients With Acute Ischaemic Stroke Receiving Intravenous Thrombolysis · Phase 3 · not yet recruiting
NCT07591207 — The Efficacy and Safety of Loxoprofen Sodium Patch in Relieving Postoperative Pain After Laparoscopic Surgery · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05197439 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Beijing Tiantan Hospital
Last refreshed: 15 June 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05197439.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing