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NCT05197140

Role of the Protein Matrix in the Anabolic Response to a Ground Beef Patty as Opposed to the Impossible (Vegi-) Burger

Completed NA Results posted Last updated 5 August 2024
What this trial tests

NA trial testing food: cooked 85% lean ground beef in Protein Metabolism in 33 participants. Completed in 3 November 2022.

Timeline
1 May 2022
Primary endpoint
3 November 2022
3 November 2022

Quick facts

Lead sponsorUniversity of Arkansas
PhaseNA
StatusCompleted
Study typeINTERVENTIONAL
Allocationrandomized
Designparallel
Maskingsingle
Primary purposebasic science
Enrollment33
Start date1 May 2022
Primary completion3 November 2022
Estimated completion3 November 2022
Sites1 location across United States

Drugs / interventions tested

Conditions studied

Sponsor

University of Arkansas

Who can join

Adults 18 to 40, any sex, with Protein Metabolism. Patients with the condition only — healthy volunteers not accepted.

Results — posted to ClinicalTrials.gov

Per-arm endpoint measurements with 95% confidence intervals where reported. Source: trial results section.

Postprandial Plasma Essential Amino Acid Concentration Incremental Area-under-the-curve [ Time Frame: 360 Minutes] Primary · 6 hours after consumption of intervention

Free leucine, isoleucine, valine, histidine, lysine, methionine, phenylalanine, threonine, tryptophan (combined) (µmol·L\^(-1)·min). Following time points (in minutes) post-ingestion will be used to calculate the incremental area under the curve: 60, 90, 120, 180, 210, 240, 270, 300, 330, 360.

GroupValue95% CI
4 Ounce Beef Patty117896± 45787
4 Ounce Vegetarian Burger75098± 45231
2x 4 Ounce Vegetarian Burger94058± 27252

Sponsor's own description

Several of the investigator's recent studies have shown that all dietary proteins are not equal when it comes to making proteins in human bodies. Generally, foods made from animal muscle tissue are much more efficient at making new proteins in the body that those from plant sources. This study will measure the amount of protein growth in participants after consuming either one beef patty, one vegi-burger, or two vegi-burgers. By using stable isotope infusions and collecting blood and leg muscle samples, the investigator's lab can determine the rate of muscle metabolism that happens after a participant eats a protein-containing food. The investigator wants to determine if the vegi-burger is as efficient as the beef patty at creating proteins in a participants. The investigator will measure this metabolism over a 10-hour period, with the food being eaten at the 4 hour mark. The investigator plans to perform this procedure on up to 8 participants per food option (24 total).

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. The anabolic response to a ground beef patty and soy-based meat alternative: a randomized controlled trial.
    Church DD, Hirsch KR, Kviatkovsky SA, Matthews JJ, et al · · 2024 · cited 8× · PMID 39222687 · DOI 10.1016/j.ajcnut.2024.08.030

Verify or expand the search:

Other recruiting trials for Protein Metabolism

Currently open trials in the same condition.

Other University of Arkansas trials

Trials by the same sponsor.

Verify against primary sources

Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05197140.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing