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NCT05196750
Effect of Obstetric Anesthesia and Delivery Mode On Neurodevelopmental And Behavioural Outcomes In A Population-Based Birth Cohort
trial testing Behavioural questionnaires and assessments on mother and child in Neurodevelopmental Disorders in 1,176 participants. Completed in 21 June 2023.
21 June 2023
Quick facts
| Lead sponsor | National University Hospital, Singapore |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 1,176 |
| Start date | 1 August 2021 |
| Primary completion | 21 June 2023 |
| Estimated completion | 21 June 2023 |
| Sites | 2 locations across Singapore |
Drugs / interventions tested
- Behavioural questionnaires and assessments on mother and child
Conditions studied
- Neurodevelopmental Disorders — all drugs for Neurodevelopmental Disorders →
- Behavior — all drugs for Behavior →
Sponsor
National University Hospital, Singapore
Who can join
Adults 0 to 10, any sex, with Neurodevelopmental Disorders or Behavior. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The study aims to determine: 1. The association between Obstetric anesthesia events at delivery (such as mode of anesthesia, drugs given, desaturation and hypotension) on pediatric neurodevelopmental and behavioural outcomes. 2. Mode of delivery on pediatric neurodevelopmental and behavioural outcomes. 3. Effect of labour epidural analgesia on neurodevelopmental and behavioural outcomes. 4. To determine if these would differ between very preterm, moderate preterm, late preterm and term infants. The study team hypothesise that: 1. Adverse maternal events during anesthesia and labor analgesia may be associated with poorer neurodevelopmental outcomes in infants. 2. Delivery via a lower segment caesarean section (LSCS) combined with a general anesthetic during delivery may be associated with adverse pediatric neurodevelopmental and behavioural outcomes. 3. The use of labour epidural analgesia is associated with poorer neurodevelopmental and behavioural outcomes. 4. These differences may be more pronounced in preterm infants as compared to term infants.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT05196750
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05196750 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by National University Hospital, Singapore
- Last refreshed: 27 July 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05196750.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing