NCT05193097 is a clinical trial in Anesthesia, sponsored by Jakob Højlund.

Who is sponsoring NCT05193097?

NCT05193097 is sponsored by Jakob Højlund.

What condition does NCT05193097 study?

NCT05193097 studies Anesthesia.

Is NCT05193097 still recruiting?

NCT05193097 is currently status unknown. Last updated 14 January 2022.

Last reviewed 2022-01-14 · How we verify

NCT05193097

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Vasopressor Preload Modulation During General Anaesthesia

Status unknown Last updated 14 January 2022

What this trial tests

trial in Anesthesia in 20 participants. Status unknown.

Timeline

3 January 2022

Primary endpoint
31 March 2023

31 March 2023

Quick facts

Lead sponsor	Jakob Højlund
Status	Status unknown
Study type	OBSERVATIONAL
Enrollment	20
Start date	3 January 2022
Primary completion	31 March 2023
Estimated completion	31 March 2023

Conditions studied

Anesthesia — all drugs for Anesthesia →

Sponsor

Jakob Højlund

Who can join

18 and older, any sex, with Anesthesia. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Is is debated whether administration of pure vasopressor may augment cardiac output (CO) by means of preload modulation. We wish to test this in 20 patients under general anesthesia, with preload dependency induced by head-up-tilt and preload modulation with infusion of phenylephrine. To document any changes in CO the patients will be monitored by Lithium dilution method. Furthermore we will monitor changes in peripheral perfusion index and test the ability of this non-invasive modality to track changes in CO.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Vasoconstriction with phenylephrine increases cardiac output in preload dependent patients.
Højlund J, Cihoric M, Foss NB. · · 2024 · cited 3× · PMID 38907106 · DOI 10.1007/s10877-024-01186-7
Vasoconstriction with Phenylephrine increases Cardiac Output in Preload Dependent Patients
Højlund J, Cihoric M, Foss NB. · · 2024 · DOI 10.21203/rs.3.rs-4277715/v1

Verify or expand the search:

Other recruiting trials for Anesthesia

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NCT07443254 — Prospective IR-led Sedation Feasibility · Phase 1, PHASE2 · recruiting

Other Jakob Højlund trials

Trials by the same sponsor.

NCT05189431 — Peripheral Perfusion Index During Induction of Anaesthesia · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05193097 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Jakob Højlund
Last refreshed: 14 January 2022

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05193097.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing