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Application of 68Ga-Pentixafor PET/CT in Primary Aldosteronism and Pre-postoperative of SAAE
Primary aldosteronism is the most common cause of secondary hypertension. The two main types of primary aldosteronism are aldosteronoma(30%) and adrenal hyperplasia(60%). The gold standard that determines the diagnosis and treatment strategy of primary aldosteronism is adrenal vein sampling(AVS), but the success rate is only about 80%. Using CXCR4 as a probe for 68Ga-Pentixafor PET/CT imaging can guide the classification diagnosis and treatment strategy of primary aldosteronism, which is a favorable supplement to AVS. Superselective adrenal artery embolization(SAAE) and laparoscopy are the main operation treatments for primary aldosteronism. SAAE is an invasive interventional operation. It is a novel way to evaluate the changes in the structure and function of adrenal tissue pre-postoperative SAAE by using the changes in 68Ga-Pentixafor PET/CT imaging.
Details
| Lead sponsor | First Affiliated Hospital of Fujian Medical University |
|---|---|
| Phase | NA |
| Status | UNKNOWN |
| Enrolment | 100 |
| Start date | Tue Sep 01 2020 00:00:00 GMT+0000 (Coordinated Universal Time) |
| Completion | Sun Sep 01 2024 00:00:00 GMT+0000 (Coordinated Universal Time) |
Conditions
- Positron-Emission Tomography
Interventions
- 68Ga-Pentixafor
Countries
China