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NCT05187962
Differential Sensory Block During Labor Epidural Analgesia: a Prospective Observational Study to Investigate the Relationship of Lower and Upper Sensory Block Levels to Cold With Sensory Block to Pinprick and Light Touch
trial in Labor Pain in 30 participants. Completed in 27 July 2022.
27 July 2022
Quick facts
| Lead sponsor | Samuel Lunenfeld Research Institute, Mount Sinai Hospital |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 30 |
| Start date | 21 December 2021 |
| Primary completion | 27 July 2022 |
| Estimated completion | 27 July 2022 |
| Sites | 1 location across Canada |
Conditions studied
- Labor Pain — all drugs for Labor Pain →
Sponsor
Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Who can join
Adults 18 to 60, female only, with Labor Pain. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Epidural analgesia remains the gold standard for pain control during labor and delivery. Proper assessment of an epidural's level of blockade is important for providing safe and effective analgesia. Previous studies have established that the most commonly tested modality for adequacy of epidural blockade is a patient's sensory blockade to cold temperature. In a study performed at our institution, Soares et. al. (publication pending) documented two thresholds of sensory block to ice: one defined as the lower sensory block level, in which the patient is able to notice the cold sensation but perceives that it is not as cold as a control dermatome; the other defined as the upper sensory block level, in which the patient perceives that the cold sensation is at approximately the same temperature as if it were applied to a non-anesthetized area such as the neck or face. Although this a known finding to nurses and physicians assessing the sensory block to ice, this phenomenon and its magnitude has not been previously reported in epidural anesthesia. The goal of this study is to examine patients with labour epidurals and to determine the dermatomal relationship between the lower and upper sensory block levels to cold when compared with sensory blockade to both pinprick and light touch.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Differential sensory block during labour epidural analgesia: a prospective observational study to investigate the relationship of lower and upper sensory block levels to cold, pinprick, and light touch.
Casellato JF, Balki M, Wang A, Ye XY, et al · · 2024 · cited 6× · PMID 38291174 · DOI 10.1007/s12630-023-02638-5
Verify or expand the search:
- PubMed search for NCT05187962
- Europe PMC full search
- ASCO Meeting Library
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Related trials
Other recruiting trials for Labor Pain
Currently open trials in the same condition.
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- NCT07401147 — Transcutaneous Electrical Nerve Stimulation (TENS) for Pain Management During Labor. · NA · recruiting
- NCT07395934 — Comparing PIEB and CEI for Labor Pain Relief · NA · recruiting
- NCT06819579 — Exploring the Optimal Concentration of Lidocaine Test Dose for Labor Analgesia · NA · active not recruiting
Other Samuel Lunenfeld Research Institute, Mount Sinai Hospital trials
Trials by the same sponsor.
- NCT06589687 — The Patient AS EDUcator in Anesthesia: Exploring the Patients' Experience During and After Unexpected Cesarean Delivery · completed
- NCT06589661 — The Patient AS EDUcator in Anesthesia: Exploring the Patients' Experience During and After Unexpected Cesarean Delivery · completed
- NCT06368583 — The Patient AS EDUcator in Anesthesia: Exploring the Patients' and Providers' Experience During Neuraxial Labour Analges · completed
- NCT06368570 — The Patient AS EDUcator in Anesthesia: Exploring the Patients' Experience During Routine Cesarean Delivery · completed
- NCT06318715 — Modified Deep Extubation vs. Standard Awake Extubation · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05187962 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Samuel Lunenfeld Research Institute, Mount Sinai Hospital
- Last refreshed: 25 October 2022
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05187962.
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