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NCT05186220: DINERVAPACE
Cardioneuroablation Versus Pacemaker Implantation for the Treatment of Symptomatic Sinus Node Dysfunction
NA trial testing Cardioneuroablation in Sinus Node Dysfunction in 40 participants. Status unknown.
1 November 2023
Quick facts
| Lead sponsor | Hospital Clinico Universitario de Santiago |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | treatment |
| Enrollment | 40 |
| Start date | 1 November 2021 |
| Primary completion | 1 November 2023 |
| Estimated completion | 1 November 2023 |
| Sites | 1 location across Spain |
Drugs / interventions tested
- Cardioneuroablation
- Permanent dual chamber pacemaker implantation
Conditions studied
- Sinus Node Dysfunction — all drugs for Sinus Node Dysfunction →
- Sick Sinus Syndrome — all drugs for Sick Sinus Syndrome →
Sponsor
Hospital Clinico Universitario de Santiago
Who can join
Adults 40 to 80, any sex, with Sinus Node Dysfunction or Sick Sinus Syndrome. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Endocardial ganglion plexus ablation (cardioneuroablation) represents a promising therapeutic technique for the treatment of vasovagal syncope (VV), functional atrioventricular block (AVB) and sinus node dysfunction (SND) with a component of vagal hypertonia. Nevertheless, there is currently a paucity of literature about the results according to the type of presentation (VV, AVB or SND). The investigators aim to assess the safety and efficacy of cardioneuroablation for the treatment of symptomatic SND.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT05186220
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Cardioneuroablation
Trials testing the same drug.
- NCT07468383 — Basic and Clinical Study of Cardiac Ganglion Catheter Ablation for the Treatment of Significant Bradycardia · NA · recruiting
- NCT06159764 — National Registry of Cardioneuroablation in Recurrent Reflex Syncope · recruiting
- NCT05896592 — Comparison of the Efficacy and Safety of Cardioneuroablation to Permanent Pacing in Patients With an Implanted Pacemaker · NA · recruiting
- NCT06472102 — Cardioneuroablation: Fragmented Atrial Potentials, Intracardiac Echocardiography and Computed Tomography · NA · recruiting
- NCT06458140 — Cardioneuroablation and Ventricular Proarrhythmia · NA · recruiting
Other recruiting trials for Sinus Node Dysfunction
Currently open trials in the same condition.
- NCT07209852 — Safety, Performance, and Clinical Benefit of Pacing the Left Bundle Branch Area - Post-Market Clinical Follow-up · recruiting
Other Hospital Clinico Universitario de Santiago trials
Trials by the same sponsor.
- NCT07495436 — Video Versus Direct Laryngoscopy for Tracheal Intubation in Pediatric Surgery · NA · not yet recruiting
- NCT07347158 — Effectiveness of Health Education as a Nursing Intervention in Improving Quality of Life and Reducing Symptoms of Anxiet · NA · enrolling by invitation
- NCT06401486 — DOuble-Lumen Intubation With VIdeolaryngoscopy · NA · completed
- NCT06725966 — Personalized Treatment of Refractory BPPV · NA · recruiting
- NCT06322719 — Hyperangulated vs Macintosh Blades for Intubation With Videolaryngoscopy in ICU · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05186220 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Hospital Clinico Universitario de Santiago
- Last refreshed: 11 January 2022
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05186220.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing