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NCT05183061

Factors Associated With Post-induction Hypotension in iNPH Patient Undergoing VP and LP Shunt

Completed Last updated 10 January 2022
What this trial tests

trial testing Ehedrine Norepineprine in The iNPH Patients Scheduled for VP or LP Shunt Procedures in 426 participants. Completed in 20 December 2021.

Timeline
1 June 2021
Primary endpoint
30 November 2021
20 December 2021

Quick facts

Lead sponsorMahidol University
StatusCompleted
Study typeOBSERVATIONAL
Enrollment426
Start date1 June 2021
Primary completion30 November 2021
Estimated completion20 December 2021
Sites1 location across Thailand

Drugs / interventions tested

Conditions studied

Sponsor

Mahidol University

Who can join

18 and older, any sex, with The iNPH Patients Scheduled for VP or LP Shunt Procedures. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This study is a retrospective work involving the review of patients who were scheduled for VP or LP shunt in Siriraj Hospital, Mahidol University, Thailand. The sample size calculation was based on the rule of thumbs of the logistic regression comprising 18 risk factors. The incidence of post-induction hypotension according to our institution's pilot study November 2019-January 2020) was 47%. With 10% addition for missing data and other possible reasons, the sample size was 426. The primary objective of the study is to report the factors associated with post-induction hypotension in iNPH patients undergoing VP or LP shunt procedures. Our secondary objective is to determine the incidence of post-induction hypotension in these patients.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

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Other Mahidol University trials

Trials by the same sponsor.

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