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Repeat BCG Vaccinations For The Treatment Of Pediatric Type 1 Diabetes
The purpose of this study is to investigate if repeat bacillus Calmette-Guérin (BCG) vaccinations can confer a beneficial immune and metabolic effect on pediatric Type 1 diabetes.
Details
| Lead sponsor | Massachusetts General Hospital |
|---|---|
| Phase | Phase 2 |
| Status | RECRUITING |
| Enrolment | 150 |
| Start date | 2022-03-22 |
| Completion | 2027-03 |
Conditions
- Diabetes Mellitus, Type 1
- Diabetes type1
- Autoimmune Diabetes
Interventions
- Bacillus Calmette-Guérin
- Saline Injection
Primary outcomes
- Change in HbA1c values — 1, 1.5, 2, 2.5, 3, 3.5, 4, 4.5, and 5 years after initial BCG/placebo injection
A change in hemoglobin A1c (HbA1c) values for pediatric type 1 diabetics compared to self.
Countries
United States