NCT05178992 is a Phase 1, PHASE2 clinical trial of Socially Assistive Robot Activity in Alzheimer Disease, sponsored by Vanderbilt University.

Who is sponsoring NCT05178992?

NCT05178992 is sponsored by Vanderbilt University.

What drugs are being tested in NCT05178992?

Interventions in NCT05178992: Socially Assistive Robot Activity.

What condition does NCT05178992 study?

NCT05178992 studies Alzheimer Disease.

Is NCT05178992 still recruiting?

NCT05178992 is currently completed. Last updated 17 February 2026.

Last reviewed 2026-02-17 · How we verify

NCT05178992

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Use of Socially Assistive Robots for Long Term Care Older Adults With Cognitive Impairment and Apathy

Completed Phase 1, PHASE2 Last updated 17 February 2026

What this trial tests

Phase 1, PHASE2 trial testing Socially Assistive Robot Activity in Alzheimer Disease in 142 participants. Completed in 31 January 2026.

Timeline

13 September 2021

Primary endpoint
31 October 2025

31 January 2026

Quick facts

Lead sponsor	Vanderbilt University
Phase	Phase 1, PHASE2
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	treatment
Enrollment	142
Start date	13 September 2021
Primary completion	31 October 2025
Estimated completion	31 January 2026
Sites	1 location across United States

Drugs / interventions tested

Socially Assistive Robot Activity

Conditions studied

Alzheimer Disease — all drugs for Alzheimer Disease →

Sponsor

Vanderbilt University

Who can join

65 and older, any sex, with Alzheimer Disease. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The objective of this study is to demonstrate the impact of a socially assistive robot system on reducing apathy among cognitively impaired older adults residing in long term care facilities. Earlier phases of this project demonstrated the feasibility and acceptability of the robotic system. First, investigators will improve the social robotic interaction architecture through additional software development, enhance its versatility, and make it easy for non-experts to run. Second, 188 participants will be randomized to either usual activity programs at the long term care facility, or the usual activity programs plus the robotic activities. Researchers will examine the effect on apathy and also plan on examining underlying individual and facility factors that influence the impact of the robotic activities.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Engaging Older Adults and Staff in the Co-Design and Evaluation of Socially Assistive Robot and Virtual Reality Activities for Long-Term Care: User-Centered Study.
Ghosh R, Khan N, Migovich M, Tate JA, et al · · 2025 · PMID 41330571 · DOI 10.2196/75288

Verify or expand the search:

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Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05178992 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Vanderbilt University
Last refreshed: 17 February 2026

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05178992.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing