NCT05177965 (OPTI-SHIFT) is a clinical trial of Exposure to shift work in Shift Work Schedule, sponsored by Tinh-Hai Collet, MD.

Who is sponsoring NCT05177965?

NCT05177965 is sponsored by Tinh-Hai Collet, MD.

What drugs are being tested in NCT05177965?

Interventions in NCT05177965: Exposure to shift work.

What condition does NCT05177965 study?

NCT05177965 studies Shift Work Schedule.

Is NCT05177965 still recruiting?

NCT05177965 is currently completed. Last updated 18 November 2025.

Last reviewed 2025-11-18 · How we verify

NCT05177965: OPTI-SHIFT

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

The Metabolic and Circadian Effects of Shift Work

Completed Last updated 18 November 2025

What this trial tests

trial testing Exposure to shift work in Shift Work Schedule in 72 participants. Completed in 30 August 2024.

Timeline

1 February 2022

Primary endpoint
30 August 2024

30 August 2024

Quick facts

Lead sponsor	Tinh-Hai Collet, MD
Status	Completed
Study type	OBSERVATIONAL
Enrollment	72
Start date	1 February 2022
Primary completion	30 August 2024
Estimated completion	30 August 2024
Sites	1 location across Switzerland

Drugs / interventions tested

Exposure to shift work

Conditions studied

Shift Work Schedule — all drugs for Shift Work Schedule →

Sponsor

Tinh-Hai Collet, MD

Who can join

Adults 20 to 50, any sex, with Shift Work Schedule. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

In an exploratory observational pilot study, the investigators will focus on the effects of short-term circadian misalignment induced by shift work on multidimensional measurements including glucose excursion, metabolic health, circadian rhythms (measured in vitro and in vivo), sleep/wake cycles and ambient light, eating and activity patterns, well-being and attention.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

The nutritional and metabolic impact of night shift work in a real-world setting
Jassil FC, Phillips NE, Hemmer A, Joris C, et al · · 2025 · DOI 10.1101/2025.10.19.25338338

Verify or expand the search:

Other Tinh-Hai Collet, MD trials

Trials by the same sponsor.

NCT04618133 — Time-restricted Eating in Morning Chronotype · NA · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05177965 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Tinh-Hai Collet, MD
Last refreshed: 18 November 2025

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05177965.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing