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NCT05176652

Ultrasonographic Diameter of Optic Nerve Sheath in Fluid Assessment in Severe Preeclamptic Patients

Status unknown Last updated 4 January 2022
What this trial tests

trial testing ultrasound in Severe Pre-eclampsia in 100 participants. Status unknown.

Timeline
6 December 2021
Primary endpoint
6 October 2022
6 December 2022

Quick facts

Lead sponsorSohag University
StatusStatus unknown
Study typeOBSERVATIONAL
Enrollment100
Start date6 December 2021
Primary completion6 October 2022
Estimated completion6 December 2022
Sites3 locations across Egypt

Drugs / interventions tested

Conditions studied

Sponsor

Sohag University

Who can join

Adults 18 to 40, female only, with Severe Pre-eclampsia. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Changes in the optic nerve sheath diameter detected by ultrasound are considered an important manifestation of increased intracranial pressure . The normal optic nerve sheath diameter measures up to 5.0 mm and an average optic nerve sheath diameter more than 5 mm is considered abnormal and elevated intracranial pressure should be suspected.Cerebral edema have been demonstrated in 71% to 100% of magnetic resonance imaging in preeclamptic patients and an increase in optic nerve sheath diameter has been described in preeclamptic females compared to healthy pregnant females Therefore, Increased optic nerve sheath diameter can indirectly reflect the state of intracranial edema that could be a part of generalized edema of preeclampsia and it could be a possible marker of generalized tissue edema and fluid overload in these patients.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

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Trials testing the same drug.

Other Sohag University trials

Trials by the same sponsor.

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