Last reviewed · How we verify
NCT05167890
Impact of Coffee vs Orange Juice on Enhancing Recovery After Laparoscopic Colorectal Surgery
NA trial testing Coffee in Colorectal Surgery in 80 participants. Status unknown.
22 January 2023
Quick facts
| Lead sponsor | National Cancer Institute, Egypt |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 80 |
| Start date | 22 November 2021 |
| Primary completion | 22 January 2023 |
| Estimated completion | 25 January 2023 |
| Sites | 1 location across Egypt |
Drugs / interventions tested
- Coffee
- Orange juice — full drug profile →
Conditions studied
- Colorectal Surgery — all drugs for Colorectal Surgery →
Sponsor
National Cancer Institute, Egypt
Who can join
Adults 20 to 75, any sex, with Colorectal Surgery. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Colorectal surgery, even performed by laparoscopy is followed by a transient episode of GI hypomotility, which results in a postoperative ileus (POI). The usual duration of this benign postoperative situation varies between 3 and 5 days for colon surgery. A longer duration of POI will result in more postoperative complications such as delayed surgical wound healing, atelectasis, pneumonia, and deep vein thrombosis; in a prolonged hospital stay; and increased healthcare cost. Different studies reported that the duration of POI correlates with total surgery time, blood loss, total opiate dose degree of surgical trauma, and bowel manipulation. Many attempts have been made to reduce the phase of postoperative intestinal hypomotility. The different strategies are well described in enhanced recovery and fast-track concepts and focus on minimal surgical trauma, rapid postoperative mobilization, early feeding, preemotive laxative treatment, restrictive fluid management, and minimal postoperative opioid prescription. Furthermore, several pharmacologic agents have been evaluated; however, not all offered a convincing benefit, nor were they free of adverse effects. Coffee is a worldwide highly consumed beverage, offering pleasure to many people of different cultures, and which many associate with an increase of bowel function. The aim of this study is to compare the time to first bowel movement after laparoscopic colorectal surgery between patients drinking coffee or orange juice postoperatively, in a randomized controlled trial (RCT).
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT05167890
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Coffee
Trials testing the same drug.
- NCT07159152 — Effects of Coffee Versus Hibiscus Tea Consumption During Prolonged Sitting on Blood Pressure and Heart Rate · NA · not yet recruiting
- NCT07420699 — The Acute Effects of Specialty Coffee on Cognitive Function in People With Type 2 Diabetes · NA · completed
- NCT06028659 — Investigation of in Vivo Endogenous and/or Exogenous Production of Phenolic Metabolites Using (un)Targeted Metabolomics · NA · recruiting
- NCT07002307 — The Effect of Honey-sweetened Coffee, Black Tea and Green Tea on Some Physiological Parameters · NA · completed
- NCT05709847 — The Effects of Specialty Coffee on Cognitive Function in People With Type 2 Diabetes · NA · unknown
Other recruiting trials for Colorectal Surgery
Currently open trials in the same condition.
- NCT07388953 — Peripheral Autonomic Block (BAP) Plus Transversus Abdominis Plane Block (TAP) for Postoperative Analgesia After Minimall · NA · recruiting
- NCT07486570 — Anastomotic Leakage Prevention by Endovascular Stenting of the Superior Mesenteric Artery · NA · recruiting
- NCT07208786 — Pre-emptive Endoscopic Vacuum Therapy Reduces the Incidence of Anastomotic Leakage After Colorectal Cancer Surgery · NA · recruiting
- NCT07065994 — The Effect of Virtual Reality Glasses Application on Pain and Anxiety Levels in Colorectal Surgery Patients · NA · active not recruiting
- NCT06850688 — Impact of Ambulatory Continuous Monitoring Using Remote Monitoring Medicine Within Patient's Care Pathway Following Colo · NA · recruiting
Other National Cancer Institute, Egypt trials
Trials by the same sponsor.
- NCT07424638 — Interscalene Block Versus Anterior Suprascapular Block for Post-Thoracotomy Shoulder Pain · NA · recruiting
- NCT07367568 — Costotransverse Foramen Block With Erector Spinae Plane Block in Modified Radical Mastectomy · NA · recruiting
- NCT07367581 — Costotransverse Foramen Block Versus Thoracic Paravertebral Block in Thoracotomy for Lung Cancer · NA · recruiting
- NCT07337330 — Ultrasound Guided External Oblique Intercostal Plane Block Versus Erector Spinae Block for Post Hepatectomy Pain · NA · not yet recruiting
- NCT07390448 — Rhomboid Intercostal Sub-serratus Plane Blocks and Erector Spinae Plane Block in Mastectomy Surgeries · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05167890 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by National Cancer Institute, Egypt
- Last refreshed: 22 December 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05167890.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing