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Treatment of Blepharitis With Povidone-Iodine 1% : a Randomized Controlled Trial
One hundred blepharitis patients will be recruited. Each patient will treat one eye once daily with 1% PVI for 30 days by scrubbing the eyelid margin with the solution. The fellow eye will serve as the control and be given the standard treatment (commercial eye wipes). Before treatment initiation, various ocular surface variables will be assessed, such as dry eye grading, subjective discomfort scales, ocular surface questionnaire, and other clinical signs. After 30 days, an identical evaluation will be performed.
Details
| Lead sponsor | Shaare Zedek Medical Center |
|---|---|
| Phase | NA |
| Status | UNKNOWN |
| Enrolment | 100 |
| Start date | 2021-08-16 |
| Completion | 2022-12 |
Conditions
- Anterior Blepharitis
Interventions
- Povidone-Iodine 1 % Topical Solution
- Eyelid cleansing wipes
Primary outcomes
- Blepharitis signs on slit-lamp examination — Day 0 (recruitment)
0-4 grading of each sign (normal, mild, moderate, severe, very severe): eyelid edema, eyelid erythema, scaling and crusting, meibomian glands clogging. - Blepharitis signs on slit-lamp examination — Day 30 (follow-up)
0-4 grading of each sign (normal, mild, moderate, severe, very severe): eyelid edema, eyelid erythema, scaling and crusting, meibomian glands clogging.
Countries
Israel