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NCT05160116

Influence of Timing of Switch Operation in Transposition of Great Arteries

Completed Last updated 20 July 2022
What this trial tests

trial in Transposition of Great Vessels in 151 participants. Completed in 10 June 2022.

Timeline
15 December 2021
Primary endpoint
30 April 2022
10 June 2022

Quick facts

Lead sponsorBrugmann University Hospital
StatusCompleted
Study typeOBSERVATIONAL
Enrollment151
Start date15 December 2021
Primary completion30 April 2022
Estimated completion10 June 2022
Sites1 location across Belgium

Conditions studied

Sponsor

Brugmann University Hospital

Who can join

Under 1, any sex, with Transposition of Great Vessels. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Transposition of great vessels are usually corrected by an arterial switch operation. This operation is often done during the first week of life as surgical delays lead to deconditioned left ventricle. On the other hand early surgery carries also risks as neonatal physiology may have problems adapting to an intervention under cardiopulmonary bypass, possible pulmonary hypertension. Arterial switch operation between 2008 and 2020 done at our center will be reviewed. Primary outcome will be mortality or severe postoperative morbidity. Patients will be divided in 2 groups according to the presence or absence of the primary outcome. After propensity score matching, they will be analysed according to the timing of operation.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

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Other recruiting trials for Transposition of Great Vessels

Currently open trials in the same condition.

Other Brugmann University Hospital trials

Trials by the same sponsor.

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Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05160116.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing