NCT05158998 is a Phase 4 clinical trial of propofol infusion in Delirium in Old Age, sponsored by Qianfoshan Hospital.

Who is sponsoring NCT05158998?

NCT05158998 is sponsored by Qianfoshan Hospital.

What drugs are being tested in NCT05158998?

Interventions in NCT05158998: propofol infusion, sevoflurane inhalation.

What condition does NCT05158998 study?

NCT05158998 studies Delirium in Old Age, Anaesthetic.

Is NCT05158998 still recruiting?

NCT05158998 is currently status unknown. Last updated 2 June 2022.

Last reviewed 2022-06-02 · How we verify

NCT05158998

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Impact of Propofol Versus Sevoflurane on Incidence of Postoperative Delirium in Elderly Patients After Spine Surgery

Status unknown Phase 4 Last updated 2 June 2022

What this trial tests

Phase 4 trial testing propofol infusion in Delirium in Old Age in 298 participants. Status unknown.

Timeline

21 March 2022

Primary endpoint
1 November 2024

1 December 2024

Quick facts

Lead sponsor	Qianfoshan Hospital
Phase	Phase 4
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	triple
Primary purpose	other
Enrollment	298
Start date	21 March 2022
Primary completion	1 November 2024
Estimated completion	1 December 2024
Sites	2 locations across China

Drugs / interventions tested

propofol infusion — full drug profile →
sevoflurane inhalation

Conditions studied

Delirium in Old Age — all drugs for Delirium in Old Age →
Anaesthetic — all drugs for Anaesthetic →

Sponsor

Qianfoshan Hospital

Who can join

Adults 65 to 90, any sex, with Delirium in Old Age or Anaesthetic. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Postoperative delirium in older adults is a common and costly complication after surgery. Propofol and sevoflurane are commonly used anesthetics to maintain sedation during spine surgery, and have different sedative and anti-inflammatory effects. The aim of this trial will be compare the impact of propofol versus sevoflurane on incidence of postoperative delirium in elderly patients after spine surgery.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Impact of propofol versus sevoflurane on the incidence of postoperative delirium in elderly patients after spine surgery: study protocol of a randomized controlled trial.
Wang JH, Lv M, Zhang HX, Gao Y, et al · · 2022 · cited 2× · PMID 36042484 · DOI 10.1186/s13063-022-06687-x

Verify or expand the search:

Other trials of propofol infusion

Trials testing the same drug.

NCT05631925 — Comparison of Two Different Anesthesia Methods in IVF Procedure · Phase 4 · completed

Other recruiting trials for Delirium in Old Age

Currently open trials in the same condition.

NCT06721819 — The SCOPE Trial: Sleep, Cognition, and Pain Bundle vs. ERAS-cardiac for Postoperative Delirium · Phase 3 · recruiting
NCT06216483 — Using EMR Data and AI to Develop a Passive Digital Marker to Predict Postoperative Delirium · NA · active not recruiting
NCT06100029 — The Effect of Lavender Essential Oil for Delirium in Elderly Intensive Care Unit Patients: Study Protocol · NA · recruiting
NCT05242419 — A Study of Huperzine A Injection in Reducing Postoperative Delirium in Elderly Patients Undergoing Non-cardiac Surgery · NA · recruiting

Other Qianfoshan Hospital trials

Trials by the same sponsor.

NCT05727618 — The Effect of Pituitrin on the Patients With Pulmonary Hypertension Undergoing Cardiac Surgery · NA · suspended
NCT06837831 — Mepilex Lite Dressings for the Treatment of Acute Radiation Dermatitis of Anal Canal Skin · NA · recruiting
NCT07260760 — Clinical Comprehensive Evaluation of Neuroprotective Drugs for Acute Ischemic Stroke · not yet recruiting
NCT07362667 — A Study of the Efficacy and Safety of Bronchoscopic Airway Clearance and Amphotericin B Spraying in Patients With ABPA · recruiting
NCT07271849 — Nalbuphine Timing Effects on Hemodynamics and Analgesia in Elderly Patients · Phase 4 · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05158998 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Qianfoshan Hospital
Last refreshed: 2 June 2022

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05158998.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing