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NCT05154084: RESECT

RESECT: Improving Quality in TURBT Surgery.

Completed Last updated 14 November 2023
What this trial tests

trial testing Performance feedback and education in Bladder Cancer in 19,505 participants. Completed in 30 September 2023.

Timeline
19 April 2021
Primary endpoint
31 July 2023
30 September 2023

Quick facts

Lead sponsorBritish Urology Researchers in Surgical Training
StatusCompleted
Study typeOBSERVATIONAL
Enrollment19,505
Start date19 April 2021
Primary completion31 July 2023
Estimated completion30 September 2023
Sites1 location across United Kingdom

Drugs / interventions tested

Conditions studied

Sponsor

British Urology Researchers in Surgical Training

Who can join

16 and older, any sex, with Bladder Cancer. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Superficial bladder cancer, known as non-muscle-invasive bladder cancer (NMIBC), is the most common type of bladder cancer. It is expensive to manage and significantly impacts on patients' quality of life. This is because there is a high burden of recurrent disease after initial treatment, and need for long term surveillance for recurrence. The most important step in the diagnosis and treatment of NMIBC is the first surgical procedure called the transurethral resection of bladder tumour (TURBT). There is evidence that the quality of the TURBT operation, and the use of a single administration of bladder chemotherapy following the operation, can reduce cancer recurrence rates and progression to more invasive cancer. There is anecdotal evidence that the quality of TURBT surgery and the usage of intravesical chemotherapy varies widely between hospitals and thus may result in worse outcomes for some patients. The primary objective of the study is to determine if audit and feedback can improve the quality of TURBT surgery and if this reduces recurrence of NMIBC.

Publications & conference data

4 peer-reviewed publications reference this trial (live from Europe PMC):

  1. Audit, Feedback, and Education to Improve Quality and Outcomes in Transurethral Resection and Single-Instillation Intravesical Chemotherapy for Nonmuscle Invasive Bladder Cancer Treatment: Protocol for a Multicenter International Observational Study With an Embedded Cluster Rando
    Gallagher K, Bhatt N, Clement K, Zimmermann E, et al · · 2023 · cited 3× · PMID 37318875 · DOI 10.2196/42254
  2. Impact of audit and feedback on transurethral resection of bladder tumour quality: a monocentric post-completion evaluation of the RESECT trial.
    Orecchia L, Gerardi M, Colalillo G, Leonardis F, et al · · 2026 · PMID 41919786 · DOI 10.1111/bju.70266
  3. NS-AUA 2023 Annual Meeting Abstracts – Oncology – Bladder, Renal, Testes
    Gaba F, Gallagher K, Bhatt N, Clement K, et al · · 2023
  4. CUA 2023 Annual Meeting Abstracts - Podium Session 4: Oncology - Bladder/Kidney/Other Sunday, June 25, 2023 • 9:00-10:00.
    · 2023 · PMID 37315271 · DOI 10.5489/cuaj.8407

Verify or expand the search:

Other recruiting trials for Bladder Cancer

Currently open trials in the same condition.

Other British Urology Researchers in Surgical Training trials

Trials by the same sponsor.

Verify against primary sources

Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05154084.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing