NCT05150431 is a Phase 4 clinical trial of Parecoxib in Perioperative Care, sponsored by National Taiwan University Hospital.

Who is sponsoring NCT05150431?

NCT05150431 is sponsored by National Taiwan University Hospital.

What drugs are being tested in NCT05150431?

Interventions in NCT05150431: Parecoxib, Placebo.

What condition does NCT05150431 study?

NCT05150431 studies Perioperative Care, Chronic Post-operative Pain.

Is NCT05150431 still recruiting?

NCT05150431 is currently completed. Last updated 2 August 2023.

Last reviewed 2023-08-02 · How we verify

NCT05150431

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Optimized Acute Pain Control With Parecoxib in Uniportal Video-assisted Thoracoscopic Surgery.

Completed Phase 4 Last updated 2 August 2023

What this trial tests

Phase 4 trial testing Parecoxib in Perioperative Care in 58 participants. Completed in 1 May 2022.

Timeline

15 December 2021

Primary endpoint
1 May 2022

1 May 2022

Quick facts

Lead sponsor	National Taiwan University Hospital
Phase	Phase 4
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	double
Primary purpose	treatment
Enrollment	58
Start date	15 December 2021
Primary completion	1 May 2022
Estimated completion	1 May 2022
Sites	1 location across Taiwan

Drugs / interventions tested

Parecoxib (PARECOXIB) — full drug profile →
Placebo

Conditions studied

Perioperative Care — all drugs for Perioperative Care →
Chronic Post-operative Pain — all drugs for Chronic Post-operative Pain →

Sponsor

National Taiwan University Hospital

Who can join

20 and older, any sex, with Perioperative Care or Chronic Post-operative Pain. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Chronic pain after thoracic surgery has been a bothering problem since the era of thoracotomy. The prevalence of chronic pain no matter in thoracotomy or video-assisted thoracoscopic surgery is about 30 to 47%. Better acute pain control after thoracic surgery has been assumed to be an effective way for prevention of chronic pain. Especially in this extreme minimal invasive surgery, uniportal video-assisted thoracic surgery, more optimized perioperative analgesics should be found out. In the guideline of "enhanced recovery after surgery", less opioid is suggested. Other than opioids, there are just few parental analgesics could be used, like acetaminophen or cyclooxygenase-2(COX-2) inhibitor. In our study, the investigators would like to build up a better analgesic strategy for uniportal video-assisted thoracoscopic surgery with less opioid and less side effects.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

Verify or expand the search:

Other trials of Parecoxib

Trials testing the same drug.

NCT06315920 — Analgesic Effect of Parecoxib Versus Morphine in SCD Patients Presenting to the Emergency Department · Phase 3 · not yet recruiting
NCT06579274 — Evaluation of the Safety and Efficacy of Parecoxib in Patients With Subarachnoid Hemorrhage · Phase 2 · not yet recruiting
NCT06600282 — Bioequivalence of Two Formulations of Parecoxib in Healthy Volunteers Under Fasting Conditions · Phase 4 · not yet recruiting
NCT06304181 — Effect of Paracetamol and Mannitol Injection on Postoperative Analgesia in Patients With Thoracoscopic Lobectomy · NA · unknown
NCT06140238 — Preemptive Analgesic Efficacy of Parecoxib for Reducing Postoperative Pain in Gynecological Surgery · Phase 4 · completed

Other recruiting trials for Perioperative Care

Currently open trials in the same condition.

NCT07396636 — Machine Learning-Assisted Management of Intraoperative Hypotension for Personalized Treatment · recruiting
NCT07260890 — Paired Comparison of SVV and PVI Accuracy · recruiting
NCT07287280 — Comparing CCI and POSSUM for Predicting Oncogynecologic Surgery Complications · recruiting
NCT06962306 — Optimizing Perioperative Analgesia to Lower Pain Following Cleft Palate Surgery · Phase 4 · recruiting
NCT06857981 — Patient's Database: Prepare for Your Surgery Program · recruiting

Other National Taiwan University Hospital trials

Trials by the same sponsor.

NCT06936917 — Timing for Computed Tomography and Post-Resuscitation Care on Short-Term Outcomes in Out-of-Hospital Cardiac Arrest · not yet recruiting
NCT05396222 — A Prospective Study of the Safety and Efficacy of 3D-printed Non-rigid Biomimetic Implant in Cervical and Thoracolumbar · NA · not yet recruiting
NCT07532356 — Integrating Tumor Genomics and Urinary Exosomal Proteomics to Establish a Multi-Layer Biomarker Framework for Early Risk · not yet recruiting
NCT07317310 — The NTU JO-SMART Study · NA · not yet recruiting
NCT07382024 — Tirzepatide to Reduce rEcurrence And Burden After Ablation of Atrial Fibrillation · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05150431 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by National Taiwan University Hospital
Last refreshed: 2 August 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05150431.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing