NCT05145530

Selective Nerve Root Block With Ultrasound Guidance Improves Surgical Outcome of Selective Discectomy in Patients With Multilevel Cervical Disc Disease

Completed Phase 2, PHASE3 Last updated 4 January 2022

What this trial tests

Phase 2, PHASE3 trial testing selective anterior cervical discectomy and fusion (ACDF) in Selective Nerve Root Block in 60 participants. Completed in 30 April 2020.

Timeline

10 August 2017

Primary endpoint
30 March 2020

30 April 2020

Quick facts

Lead sponsor	Assiut University
Phase	Phase 2, PHASE3
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	triple
Primary purpose	prevention
Enrollment	60
Start date	10 August 2017
Primary completion	30 March 2020
Estimated completion	30 April 2020
Sites	1 location across Egypt

Drugs / interventions tested

• selective anterior cervical discectomy and fusion (ACDF)
• SNRB+ selective anterior cervical discectomy and fusion (ACDF)

Conditions studied

• Selective Nerve Root Block — all drugs for Selective Nerve Root Block →
• Selective Discectomy — all drugs for Selective Discectomy →

Sponsor

Assiut University

Who can join

Adults 30 to 60, any sex, with Selective Nerve Root Block or Selective Discectomy. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Disc degeneration is a natural part of growing older. Up to 60% of asymptomatic people have MRI findings that are positive. As a result, MRI only provides morphological information and may not be able to determine the clinical significance of the findings.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

1. Ultrasound-Guided Selective Nerve Root Block for Surgical Planning in Multilevel Cervical Disc Disease: A Technical Report.
   Lam KHS, Yoon Y, Su DC, Suhaimi A, et al · · 2026 · PMID 42028518 · DOI 10.7759/cureus.105690