Last reviewed · How we verify
NCT05145049
The Relationship of Anesthesia Method With Serum Lactate Level in Craniotomies
trial in Intracranial Neoplasm in 110 participants. Completed in 30 November 2022.
1 September 2022
Quick facts
| Lead sponsor | Ankara Diskapi Training and Research Hospital |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 110 |
| Start date | 1 November 2021 |
| Primary completion | 1 September 2022 |
| Estimated completion | 30 November 2022 |
| Sites | 1 location across Turkey (Türkiye) |
Conditions studied
- Intracranial Neoplasm — all drugs for Intracranial Neoplasm →
- Hyperlactatemia — all drugs for Hyperlactatemia →
- Brain Tumor — all drugs for Brain Tumor →
- Hypoperfusion — all drugs for Hypoperfusion →
Sponsor
Ankara Diskapi Training and Research Hospital
Who can join
18 and older, any sex, with Intracranial Neoplasm or Hyperlactatemia. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The investigators aimed to research the incidence of hyperlactatemia in craniotomy cases, the relationship of lactate elevation with tumor type and other factors that may be related, and whether the general anesthesia method applied (inhalation anesthesia or total ıntravenous anesthesia) affects lactate level.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Frequency of hyperlactatemia in craniotomy and its association with anesthesia: A prospective observational study.
Ozkan Sipahioglu F, Atar F, Ozhan Caparlar C, Donmez A. · · 2026 · PMID 41861163 · DOI 10.1097/md.0000000000047984
Verify or expand the search:
- PubMed search for NCT05145049
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other Ankara Diskapi Training and Research Hospital trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05145049 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Ankara Diskapi Training and Research Hospital
- Last refreshed: 16 May 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05145049.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing