Last reviewed · How we verify
NCT05144659: DFOF#TIOF
Evaluation of Double Faced Transverse Preputial Onlay Island Flap for Hypospadias Repair in Pediatrics
NA trial testing Double faced transverse preputial onlay island flap in Hypospadias in 68 participants. Completed in 28 February 2021.
30 April 2020
Quick facts
| Lead sponsor | dr. Muhammad Abdelhafez Mahmoud, MD |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | treatment |
| Enrollment | 68 |
| Start date | 1 May 2019 |
| Primary completion | 30 April 2020 |
| Estimated completion | 28 February 2021 |
| Sites | 1 location across Egypt |
Drugs / interventions tested
- Double faced transverse preputial onlay island flap
- Transverse inner preputial onlay island flap
Conditions studied
- Hypospadias — all drugs for Hypospadias →
Sponsor
dr. Muhammad Abdelhafez Mahmoud, MD
Who can join
Adults 1 to 14, male only, with Hypospadias. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Evaluation of double faced transverse preputial onlay island flap for hypospadias repair in pediatrics. The preputial onlay island flap technique has been popularized for hypospadias repair as a result of offering a consistent combination of excellent cosmetic results and acceptable complication rates. Like other techniques, urethrocutaneous fistulae continue to be the most common complications, in addition to other complications, and can be attributed to the affection of flaps vascularity. Some authors describe a technique that resolves some of these problems by combining the unique benefits of the double-faced preputial flaps. This study aimed to evaluate double faced preputial onlay island flap technique for complication rate, outcomes for urinary stream, and cosmetic results.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Evaluation of double faced transverse preputial (onlay) island flap for hypospadias repair in pediatrics: a randomized controlled study.
Daboos M, Hefney K, Abdelhafez Mahmoud M, Salama A, et al · · 2022 · cited 2× · PMID 35462581 · DOI 10.1007/s11255-022-03217-1
Verify or expand the search:
- PubMed search for NCT05144659
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Hypospadias
Currently open trials in the same condition.
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- NCT06832280 — Improving Parental Support in Hypospadias Care · NA · recruiting
- NCT06520423 — Effectiveness of Urethral Stent Irrigation in Preventing Surgical Site Infections in Adolescents With Hypospadias · NA · active not recruiting
Other dr. Muhammad Abdelhafez Mahmoud, MD trials
Trials by the same sponsor.
- NCT06113978 — Thoracoscopic Sympathetic Chain Interruption for Palmar Hyperhidrosis in Patients Below 18 · NA · completed
- NCT05957562 — Azygos Vein Preservation; Its Impact on Early Outcomes After Neonatal EA/TOF Repair · NA · completed
- NCT04990570 — Telemedicine (Virtual Clinic) for Pediatric Surgery During Covid-19 Pandemic · completed
- NCT04821167 — Safety and Efficiency of Laparoscopic Management of Intra-canalicular (Emergent) Testis · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05144659 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by dr. Muhammad Abdelhafez Mahmoud, MD
- Last refreshed: 17 December 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05144659.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing