Last reviewed · How we verify
NCT05142124: G-CAR
German Cardiac Arrest Registry
trial in Out-of-hospital Cardiac Arrest in 400 participants. Currently enrolling.
31 December 2026
Quick facts
| Lead sponsor | Leipzig Heart Science gGmbH |
|---|---|
| Status | Recruiting now |
| Study type | OBSERVATIONAL |
| Enrollment | 400 |
| Start date | 21 July 2021 |
| Primary completion | 31 December 2026 |
| Estimated completion | 30 June 2027 |
| Sites | 25 locations across Germany |
Conditions studied
- Out-of-hospital Cardiac Arrest — all drugs for Out-of-hospital Cardiac Arrest →
Sponsor
Leipzig Heart Science gGmbH
Who can join
18 and older, any sex, with Out-of-hospital Cardiac Arrest. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
In Germany, 70.000 to 100.000 patients suffer from out-of-hospital cardiac arrest (OHCA) every year. More than half of these are due to cardiac causes. Despite the medical progress over the last decades, rates of survival with good neurological outcome remain low. For many below-mentioned issues, no adequate evidence from randomized trials is available. Therefore, a systematic and standardized recording of the pre-clinical, clinical and post-clinical treatment course and of the clinical outcomes of OHCA patients is essential to improve patient care. Aim of the German Cardiac Arrest Registry (G-CAR) is to achieve a better understanding of the disease entity, leading to an optimized treatment of OHCA patients. The recorded data include information on demographic and psychosocial aspects, course of the disease, clinical, laboratory and other examinations as well as treatment modalities in patients with OHCA due to a cardiac cause.
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
German Cardiac Arrest Registry: rationale and design of G-CAR.
Pöss J, Sinning C, Schreiner I, Apfelbacher C, et al · · 2023 · cited 8× · PMID 35729429 · DOI 10.1007/s00392-022-02044-9 -
German Cardiac Arrest Registry (G-CAR)-results of the pilot phase.
Pöss J, Sinning C, Roßberg M, Hösler N, et al · · 2025 · cited 1× · PMID 38869632 · DOI 10.1007/s00392-024-02468-5
Verify or expand the search:
- PubMed search for NCT05142124
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05142124 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Leipzig Heart Science gGmbH
- Last refreshed: 12 February 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05142124.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing