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NCT05140681
Influence of Flap Position Following FibReORS
NA trial testing FibReORS with apically positioned flap (apical position) in Periodontitis in 16 participants. Completed in 23 December 2018.
31 October 2018
Quick facts
| Lead sponsor | University of Turin, Italy |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | triple |
| Primary purpose | treatment |
| Enrollment | 16 |
| Start date | 1 September 2017 |
| Primary completion | 31 October 2018 |
| Estimated completion | 23 December 2018 |
| Sites | 1 location across Italy |
Drugs / interventions tested
- FibReORS with apically positioned flap (apical position)
- FibReORS with apically positioned flap (crestal position)
Conditions studied
- Periodontitis — all drugs for Periodontitis →
- Periodontal Diseases — all drugs for Periodontal Diseases →
Sponsor
University of Turin, Italy
Who can join
18 and older, any sex, with Periodontitis or Periodontal Diseases. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
There is lack of data in literature on keratinized tissue increase after FibReORS in relation to primary flap position. This study has been designed as a split-mouth randomized trial to assess the influence of flap position after FibReORS. 16 patients were recruited and treated. The placement of the flap 2 mm apically to the bone crest instead at the bone level would be a viable approach to increase KT width without delaying wound healing. The extent of post-operative discomfort/pain was not influenced by primary flap position.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Effect of post-surgical flap position on soft tissue regrowth and keratinized tissue increase following fibre retention osseous resective surgery: a 6-month randomized study with multilevel analysis.
Piccoli GM, Romano F, Giraudi M, La Bruna N, et al · · 2023 · cited 3× · PMID 37430291 · DOI 10.1186/s12903-023-03144-2
Verify or expand the search:
- PubMed search for NCT05140681
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05140681 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Turin, Italy
- Last refreshed: 1 December 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05140681.
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