NCT05138783 is a NA clinical trial of Verofilcon A contact lenses in Refractive Errors, sponsored by Alcon Research.

Who is sponsoring NCT05138783?

NCT05138783 is sponsored by Alcon Research.

What drugs are being tested in NCT05138783?

Interventions in NCT05138783: Verofilcon A contact lenses, Nesofilcon A contact lenses.

What condition does NCT05138783 study?

NCT05138783 studies Refractive Errors.

Is NCT05138783 still recruiting?

NCT05138783 is currently completed. Last updated 18 April 2023.

Are results published for NCT05138783?

Yes — primary outcome results have been posted to ClinicalTrials.gov. See the outcomes section above for details.

Last reviewed 2023-04-18 · How we verify

NCT05138783

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Clinical Performance of Two Daily Disposable Soft Contact Lenses

Completed NA Results posted Last updated 18 April 2023

What this trial tests

NA trial testing Verofilcon A contact lenses in Refractive Errors in 129 participants. Completed in 7 March 2022.

Timeline

12 January 2022

Primary endpoint
7 March 2022

7 March 2022

Quick facts

Lead sponsor	Alcon Research
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	crossover
Masking	double
Primary purpose	treatment
Enrollment	129
Start date	12 January 2022
Primary completion	7 March 2022
Estimated completion	7 March 2022
Sites	8 locations across United States

Drugs / interventions tested

Verofilcon A contact lenses
Nesofilcon A contact lenses

Conditions studied

Refractive Errors — all drugs for Refractive Errors →

Sponsor

Alcon Research — full company profile →

Who can join

18 and older, any sex, with Refractive Errors. Patients with the condition only — healthy volunteers not accepted.

Results — posted to ClinicalTrials.gov

Per-arm endpoint measurements with 95% confidence intervals where reported. Source: trial results section.

Least Squares Mean Distance Visual Acuity (VA) With Study Lenses Primary · Day 8 (-0/+3 days), each study lens type

Visual Acuity (VA) was collected for each eye individually with study lenses in place using a letter chart. VA was measured in logarithm of the minimum angle of resolution (logMAR). A logMAR value of 0 corresponds to 20/20 Snellen acuity (normal distance eyesight), with a lower logMAR value indicating better visual acuity.

Group	Value	95% CI
PRECISION1	-0.13	± 0.006
Biotrue	-0.13	± 0.006

Sponsor's own description

The purpose of this study is to compare the clinical performance of PRECISION1 contact lenses with Biotrue contact lenses.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Silicone hydrogel versus hydrogel soft contact lenses for differences in patient-reported eye comfort and safety.
Haworth K, Travis D, Leslie L, Fuller D, et al · · 2023 · cited 10× · PMID 37724689 · DOI 10.1002/14651858.cd014791.pub2

Verify or expand the search:

Other trials of Verofilcon A contact lenses

Trials testing the same drug.

NCT04942925 — Clinical Comparison of Two Daily Disposable Contact Lenses - Pilot Study 3 · NA · completed
NCT04865354 — Clinical Comparison of Two Daily Disposable Contact Lenses · NA · completed
NCT04527978 — Clinical Comparison of 2 Daily Disposable Contact Lenses - Pilot Study 1 · NA · completed
NCT04528017 — Clinical Comparison of 2 Daily Disposable Contact Lenses - Pilot Study 2 · NA · completed
NCT04201639 — Evaluating the Performance of Precision1 Daily Disposable Contact Lens in a Group of Heavy Digital Device Users · NA · completed

Other recruiting trials for Refractive Errors

Currently open trials in the same condition.

NCT07460557 — Morphological Characteristics of the Maxillomandibular Region in a 3D Representation and the Refractive Status of the Ey · recruiting
NCT06913491 — Efficacy of PEEK Acuity Versus ETDRS Chart for Assessment of Visual Acuity and Refractive Error · active not recruiting
NCT07001124 — Comparative Efficacy of Duochrome Test Verse +1 Blur Test in Detecting Refracting Error Across Different Ages · NA · active not recruiting
NCT06668246 — Performance of Refractometers With Self-adjusting Lenses Compared to Cycloplegia in Children (REFRALENS) · active not recruiting
NCT05458323 — Cognitive Level Enhancement Through Vision Exams and Refraction · NA · recruiting

Other Alcon Research trials

Trials by the same sponsor.

NCT06884202 — Evaluation of Delefilcon A Contact Lenses · NA · completed
NCT06784063 — Visual Performance With Clareon® Vivity® Intraocular Lenses (IOLs) · NA · completed
NCT06571656 — Evaluation of the Safety and Tolerability of Ocular Lubricants · NA · terminated
NCT06660290 — A Study to Evaluate 0.003% AR-15512 Safety and Drop Attributes · Phase 3 · completed
NCT06483113 — DAILIES TOTAL1® Soft Contact Lenses - Post-Market Clinical Follow-up Study · terminated

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05138783 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Alcon Research
Last refreshed: 18 April 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05138783.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing