Last reviewed · How we verify
NCT05137977
Is Invasive ICU-treatment Associated With Mental Illness?
trial testing Intensive Care in Postintensive Care Syndrome in 1,048,576 participants. Completed in 31 December 2015.
31 December 2015
Quick facts
| Lead sponsor | Uppsala University |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 1,048,576 |
| Start date | 1 January 2010 |
| Primary completion | 31 December 2015 |
| Estimated completion | 31 December 2015 |
Drugs / interventions tested
- Intensive Care
Conditions studied
- Postintensive Care Syndrome — all drugs for Postintensive Care Syndrome →
- Anxiety Disorder — all drugs for Anxiety Disorder →
- Depression — all drugs for Depression →
- PTSD — all drugs for PTSD →
Sponsor
Uppsala University
Who can join
18 and older, any sex, with Postintensive Care Syndrome or Anxiety Disorder. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Understanding long-term complications after intensive care is important to be able to offer prophylactic and therapeutic measures to post-intensive care unit (ICU) patients. Since patients in the ICU experience life threatening conditions, severe psychological and physical stress, we hypothesized that patients after ICU have an increased risk of mental illnesses specifically anxiety disorders, depression and post-traumatic stress disorder (PTSD). Moreover, we hypothesized that the prevalence and severity of mental illnesses are related to the extent of intensive care. Our endpoints are the prevalence of anxiety disorders, depression one year after ICU-care and if the extent of intensive care an independent predictor of psychiatric illness one year after ICU admission. We will assess Swedish Intensive Care registry data for all adult ICU patients admitted between 2010-2015 and assess ICD-10 codes for anxiety disorders, depression and PTSD one year after ICU admission.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
A nationwide cohort study on the association between intensive care treatments and mental distress linked psychiatric disorders.
Mossberg R, Ahlström B, Lipcsey M. · · 2024 · cited 3× · PMID 38402361 · DOI 10.1038/s41598-024-55102-9
Verify or expand the search:
- PubMed search for NCT05137977
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other Uppsala University trials
Trials by the same sponsor.
- NCT07517185 — The HIt HArd and hiT Early in Multiple Sclerosis Trial · Phase 2 · not yet recruiting
- NCT07351149 — Postoperative Acute Kidney Injury in Children Undergoing Major Non-cardiac Surgery · recruiting
- NCT07461636 — Robotic-Assisted Pedicle Screw Placement in Spine Surgery · recruiting
- NCT07273409 — Pancreatic Neuroendocrine Tumour - Optimal Surgical Debulking or Not · NA · recruiting
- NCT07352683 — Open TAP-block in Pediatric Abdominal Surgery · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05137977 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Uppsala University
- Last refreshed: 30 November 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05137977.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing