Last reviewed · How we verify
NCT05136040
Low-Doses Of Isobaric Bupivacaine On Intraoperative Hemodynamics In Spinal Anesthesia During Cesarean Section
NA trial testing Bupivacaine in Cesarean Section in 80 participants. Completed in 15 June 2019.
15 June 2019
Quick facts
| Lead sponsor | Ataturk University |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | prevention |
| Enrollment | 80 |
| Start date | 15 October 2018 |
| Primary completion | 15 June 2019 |
| Estimated completion | 15 June 2019 |
| Sites | 1 location across Turkey (Türkiye) |
Drugs / interventions tested
- Bupivacaine (BUPIVACAINE) — full drug profile →
Conditions studied
- Cesarean Section — all drugs for Cesarean Section →
- Hemodynamic Instability — all drugs for Hemodynamic Instability →
Sponsor
Ataturk University
Who can join
Adults 18 to 50, female only, with Cesarean Section or Hemodynamic Instability. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The primary aim of this study was to compare the effects of two different low-dose bupivacaine used in spinal anesthesia on intraoperative hemodynamics in cesarean section operations.Investigators think that low-dose bupivacaine and fentanyl mixture applied in cesarean section cause fewer hemodynamic changes,provide adequate anesthesia and analgesia quality,cause fewer side effects,and postoperatively,patients may return to their daily activities more quickly.This study was conducted on 80 pregnant women undergo an elective cesarean section.Patients were randomly allocated in GrupA and GroupB. Combined spinal-epidural anesthesia was performed in the sitting position using the needle-inside-needle technique.After cerebrospinal fluid flow was observed, GroupA patients were given a solution containing 5 mg isobaric bupivacaine+15 µg fentanyl (1.3 ml),and Group B was administered a solution containing 7 mg isobaric bupivacaine+15 µg fentanyl (1.7ml).Hypotension,bradycardia,duration of analgesia,postoperative nausea and vomiting were recorded.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT05136040
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Bupivacaine
Trials testing the same drug.
- NCT05785377 — Neostigmine as an Adjuvant in Tranversus Abdominis Plane (TAP) Block in Cesarean Section Under Spinal Anesthesia · NA · not yet recruiting
- NCT07467356 — Anterior Iliopsoas Space Block Versus PENG Block on Ease of Positioning for Spinal Anathesia in Patients Undergoing Hip · Phase 3 · recruiting
- NCT07465185 — Intrathecal Bupivacaine With or Without Dexmetomidine for Cesserian Delivery · Phase 2 · recruiting
- NCT07430085 — Post-Operative Pain Relief: Zynrelef or Periarticular Injections in RATKA · Phase 4 · not yet recruiting
- NCT07146685 — Effect of Local Anesthetic Concentration on Rebound Pain: A Randomized Control Study · Phase 4 · not yet recruiting
Other recruiting trials for Cesarean Section
Currently open trials in the same condition.
- NCT07511491 — Ondansetron Lozenge Versus Intravenous for Prevention of Shivering in Cesarean Section · NA · recruiting
- NCT06282952 — Health Outcomes in C-Section Infants With Fecal Microbiota Transplantation · NA · recruiting
- NCT07499947 — Predicting Spinal Hypotension in Cesarean Section · recruiting
- NCT07413185 — Relationship Between the Severity of Sleep Deprivation in the First 48 Hours Postpartum, Breastfeeding Motivation, and B · recruiting
- NCT07440667 — Restrictive vs Liberal Intraoperative Fluid Strategy and Postoperative Outcomes After Elective Cesarean Section · NA · recruiting
Other Ataturk University trials
Trials by the same sponsor.
- NCT07518537 — Bulk-Fill Composite Restorations: Clinical Evaluation · NA · not yet recruiting
- NCT07241156 — Creative Drama on Gender Role Stress, Attitudes Toward Violence Against Women, and Aggression · NA · not yet recruiting
- NCT07451418 — The Effect of Mindfulness Compassionate Living Training on Unwanted Pregnancies · NA · not yet recruiting
- NCT07464548 — Effects of Stoma Education on Patients · NA · recruiting
- NCT07375277 — Effects Of Biceps Transposition Without Tenotomy For Augmentation Of Massive Rotator Cuff Repairs · NA · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05136040 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Ataturk University
- Last refreshed: 8 December 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05136040.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing