NCT05133310 is a Phase 4 clinical trial of Simvastatin in Strains, sponsored by Hospital General de Mexico.

Who is sponsoring NCT05133310?

NCT05133310 is sponsored by Hospital General de Mexico.

What drugs are being tested in NCT05133310?

Interventions in NCT05133310: Simvastatin.

What condition does NCT05133310 study?

NCT05133310 studies Strains, Acute Lymphoblastic Leukemia, Sepsis.

Is NCT05133310 still recruiting?

NCT05133310 is currently status unknown. Last updated 4 January 2022.

Last reviewed 2022-01-04 · How we verify

NCT05133310

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Effect of Simvastatin on Sepsis and Febrile Neutropenia in Patients With Acute Lymphoblastic Leukemia

Status unknown Phase 4 Last updated 4 January 2022

What this trial tests

Phase 4 trial testing Simvastatin in Strains in 108 participants. Status unknown.

Timeline

19 November 2021

Primary endpoint
16 December 2022

23 June 2023

Quick facts

Lead sponsor	Hospital General de Mexico
Phase	Phase 4
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	treatment
Enrollment	108
Start date	19 November 2021
Primary completion	16 December 2022
Estimated completion	23 June 2023
Sites	1 location across Mexico

Drugs / interventions tested

Simvastatin (simvastatin) — full drug profile →

Conditions studied

Strains — all drugs for Strains →
Acute Lymphoblastic Leukemia — all drugs for Acute Lymphoblastic Leukemia →
Sepsis — all drugs for Sepsis →

Sponsor

Hospital General de Mexico

Who can join

Adults 18 to 55, any sex, with Strains or Acute Lymphoblastic Leukemia. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

In general, the percentage of complete remissions is 85 - 90 % for acute lymphoid leukemia (ALL). In developing countries, percentages are lower secondary to higher sepsis-related mortality. Although the effect of statins on inflammatory response associated with sepsis has been demonstrated, including an effect on bacterial proliferation in patients with a state of immunosuppression, their effect has not been demonstrated so far in patients with hemato-oncological cancer.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

Verify or expand the search:

Other trials of Simvastatin

Trials testing the same drug.

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NCT07031778 — Topic Simvastatin for Bone Regeneration · EARLY_PHASE1 · recruiting
NCT06399783 — Topical Simvastatin Versus Topical Steroid in Treatment of Alopecia Areata · Phase 4 · not yet recruiting

Other recruiting trials for Strains

Currently open trials in the same condition.

NCT04889053 — Coronary Artery Calcification in Type 2 Diabetes Mellitus (USCAC Study) · recruiting

Other Hospital General de Mexico trials

Trials by the same sponsor.

NCT07258043 — Efficacy of Dose-Adjusted Regimen on Survival in Frail Adults With Acute Lymphoblastic Leukemia · recruiting
NCT06589973 — Effect of Clinical and Biochemical Variables Over Morbidity and Mortality in Alcohol Withdrawal Syndrome Patients · recruiting
NCT06284395 — Two Schemes Response in Multiple Myeloma · recruiting
NCT06648551 — Diagnostic Performance of Controlling Nutritional Status as a Nutritional Screening Tool in Patients With Inflammatory B · recruiting
NCT05951803 — Effectiveness of a Psychological Intervention on Mental Health and Sleep. · NA · unknown

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05133310 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Hospital General de Mexico
Last refreshed: 4 January 2022

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05133310.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing