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NCT05131776
EUS-guided Intra-tumour Injection of OncoSil for Locally Advanced Pancreatic Carcinoma.
Phase 2, PHASE3 trial testing EUS-guided oncosil injection in Pancreatic Cancer in 2 participants. Terminated before completion.
31 December 2023
Quick facts
| Lead sponsor | Chinese University of Hong Kong |
|---|---|
| Phase | Phase 2, PHASE3 |
| Status | Terminated |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 2 |
| Start date | 1 November 2021 |
| Primary completion | 31 December 2023 |
| Estimated completion | 31 December 2023 |
| Sites | 1 location across Hong Kong |
Drugs / interventions tested
- EUS-guided oncosil injection
Conditions studied
- Pancreatic Cancer — all drugs for Pancreatic Cancer →
- Endoscopic Ultrasound — all drugs for Endoscopic Ultrasound →
Sponsor
Chinese University of Hong Kong
Who can join
18 and older, any sex, with Pancreatic Cancer or Endoscopic Ultrasound. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The outcomes of concurrent EUS-guided intra-tumour injection of P-32 microparticles (OncoSil; OncoSil Medical, Australia) with chemotherapy in locally advanced pancreatic carcinoma in the local population is uncertain. The aim of the current study is to assess efficacy and safety of the intervention in the local population. We hypothesis that the intervention is safe and useful for tumour downstaging.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Clinical diagnosis and management of pancreatic cancer: Markers, molecular mechanisms, and treatment options.
Zhang CY, Liu S, Yang M. · · 2022 · cited 28× · PMID 36632312 · DOI 10.3748/wjg.v28.i48.6827
Verify or expand the search:
- PubMed search for NCT05131776
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05131776 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Chinese University of Hong Kong
- Last refreshed: 23 March 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05131776.
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