Who is sponsoring NCT05128500?

NCT05128500 is sponsored by Permedica spa.

What drugs are being tested in NCT05128500?

Interventions in NCT05128500: Total Shoulder Arthroplasty with Permedica's MIRAI.

What condition does NCT05128500 study?

NCT05128500 studies Cuff Tear Arthropathy, Primary Osteoarthritis, Secondary Osteoarthritis, Shoulder Osteoarthritis, Rheumatoid Arthritis Shoulder, Psoriatic Arthritis, Fracture, Shoulder, Avascular Necrosis of Humerus.

Is NCT05128500 still recruiting?

NCT05128500 is currently completed. Last updated 2 September 2025.

Last reviewed 2025-09-02 · How we verify

NCT05128500

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Follow-up Evaluating Clinical and Radiological Outcomes of Total Shoulder Arthroplasty With Permedica's MIRAI Prosthesis

Completed Last updated 2 September 2025

What this trial tests

trial testing Total Shoulder Arthroplasty with Permedica's MIRAI in Cuff Tear Arthropathy in 76 participants. Completed in 31 January 2025.

Timeline

12 July 2019

Primary endpoint
31 January 2025

31 January 2025

Quick facts

Lead sponsor	Permedica spa
Status	Completed
Study type	OBSERVATIONAL
Enrollment	76
Start date	12 July 2019
Primary completion	31 January 2025
Estimated completion	31 January 2025
Sites	4 locations across Italy, Switzerland, Germany

Drugs / interventions tested

Total Shoulder Arthroplasty with Permedica's MIRAI

Conditions studied

Cuff Tear Arthropathy — all drugs for Cuff Tear Arthropathy →
Primary Osteoarthritis — all drugs for Primary Osteoarthritis →
Secondary Osteoarthritis — all drugs for Secondary Osteoarthritis →
Shoulder Osteoarthritis — all drugs for Shoulder Osteoarthritis →

Sponsor

Permedica spa

Who can join

18 and older, any sex, with Cuff Tear Arthropathy or Primary Osteoarthritis. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This observational study is conducted in order to evaluate the effectiveness of the primary total shoulder arthroplasty with the Permedica's MIRAI Modular Shoulder Prosthesis System on the general population of patients who are about to undergo this surgery for every indication. Patients requiring a revision shoulder arthroplasty will not be enrolled. The effectiveness will be evaluated in terms of recovery of shoulder function and stability of the prosthetic implant. The incidence of complications, adverse and serious adverse events will also be studied. Additional study aim is to evaluate a medium/long term survival of the prosthesis. The duration of the study per single subject is 5 years.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Stemless total shoulder arthroplasty with nonspherical polyethylene humeral head.
Bloch HR, Agneskirchner J, Meyer P, Di Fabio S, et al · · 2025 · PMID 41049673 · DOI 10.1016/j.jseint.2025.05.010

Verify or expand the search:

Other Permedica spa trials

Trials by the same sponsor.

NCT05810285 — Total Knee Arthroplasty With Vitamin E Polyethylene · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05128500 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Permedica spa
Last refreshed: 2 September 2025

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05128500.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing