NCT05128136 is a NA clinical trial of Impact of ring size on adherence in Hiv, sponsored by Population Council.

Who is sponsoring NCT05128136?

NCT05128136 is sponsored by Population Council.

What drugs are being tested in NCT05128136?

Interventions in NCT05128136: Impact of ring size on adherence.

What condition does NCT05128136 study?

NCT05128136 studies Hiv, Pregnancy Related.

Is NCT05128136 still recruiting?

NCT05128136 is currently completed. Last updated 9 February 2023.

Last reviewed 2023-02-09 · How we verify

NCT05128136

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

A Crossover Study Evaluating 3 Non-medicated Silicone IVRs

Completed NA Last updated 9 February 2023

What this trial tests

NA trial testing Impact of ring size on adherence in Hiv in 48 participants. Completed in 31 January 2023.

Timeline

20 January 2022

Primary endpoint
31 December 2022

31 January 2023

Quick facts

Lead sponsor	Population Council
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	crossover
Masking	none
Primary purpose	other
Enrollment	48
Start date	20 January 2022
Primary completion	31 December 2022
Estimated completion	31 January 2023
Sites	2 locations across United States

Drugs / interventions tested

Impact of ring size on adherence

Conditions studied

Hiv — all drugs for Hiv →
Pregnancy Related — all drugs for Pregnancy Related →

Sponsor

Population Council

Who can join

Adults 18 to 40, any sex, with Hiv or Pregnancy Related. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The overall aim of this study is to assess different external diameters of intravaginal rings (IVRs) for adherence, preference, and acceptability. To assess these domains, women in male-partnered relationships will use three different size IVRs.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Development and Validation of a Multidimensional Intravaginal Ring Acceptability Scale Among US Women and Their Male Partners.
Gottert A, Friedland BA, Plagianos M, Zieman B, et al · · 2025 · cited 2× · PMID 40211751 · DOI 10.1111/psrh.70009
Preference, adherence, and acceptability of 3 nonmedicated intravaginal rings of differing external diameters: a randomized, crossover trial.
Friedland BA, Sales JM, Atrio J, Plagianos MG, et al · · 2025 · cited 1× · PMID 40064412 · DOI 10.1016/j.ajog.2025.03.001

Verify or expand the search:

Other recruiting trials for Hiv

Currently open trials in the same condition.

NCT06001814 — Mindfulness and Behavior Change to Improve Cardiovascular Health of Older People With HIV · NA · recruiting
NCT06999928 — Enhanced Mentor Mother Strategy for Pregnant and Postpartum Women Living With HIV · NA · recruiting
NCT06006143 — Off-Label Medications for Alcohol Use Disorder Among Patients With HIV: Pilot Study 2 · Phase 2 · active not recruiting
NCT07076043 — Multi-product PrEP Delivery to Young Women Seeking Reproductive Health Services and Coverage of HIV Prevention · Phase 4 · recruiting
NCT06389565 — Change My Story Task Shifted Mental Health Intervention · NA · recruiting

Other Population Council trials

Trials by the same sponsor.

NCT07039591 — Assess Performance Attributes and Acceptability of Non-medicated Intravaginal Rings Among Sexually Active Women in Atlan · EARLY_PHASE1 · recruiting
NCT04778514 — A Crossover Acceptability Study Assessing a DPP Capsule for HIV and Pregnancy Prevention · NA · completed
NCT05644886 — Pilot Study on Engaging Family Physicians in Family Planning in Pakistan · NA · unknown
NCT04778527 — A Crossover Adherence and Acceptability Study Assessing a DPP Capsule for HIV and Pregnancy Prevention · NA · unknown
NCT02875119 — Study to Evaluate the Safety of Griffithsin in a Carrageenan Gel in Healthy Women · Phase 1 · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05128136 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 9 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Population Council
Last refreshed: 9 February 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05128136.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing