Last reviewed · How we verify
NCT05123014
Lenticule Implantation and Autologous Serum New Approach in Treatment of Adenoviral Keratitis Disease
NA trial testing relex smile in Adenoviral Keratoconjunctivitis in 45 participants. Participants enrolled and being followed up; not accepting new ones.
1 February 2019
Quick facts
| Lead sponsor | Eye Hospital Pristina Kosovo |
|---|---|
| Phase | NA |
| Status | Active, enrolled |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 45 |
| Start date | 1 February 2018 |
| Primary completion | 1 February 2019 |
| Estimated completion | 1 February 2027 |
| Sites | 1 location across Kosovo |
Drugs / interventions tested
- relex smile
Conditions studied
- Adenoviral Keratoconjunctivitis — all drugs for Adenoviral Keratoconjunctivitis →
Sponsor
Eye Hospital Pristina Kosovo
Who can join
Adults 24 to 43, any sex, with Adenoviral Keratoconjunctivitis. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Adenoviral keratitis(caused by adenovirus) is one of the most frequently diagnosed eye diseases. Most of these infections have symptoms like (Ocular itchiness and irritation, chemosis (conjunctival edema),photophobia, epiphora, foreign body sensation, epithelial keratitis etc.Adenoviral subepithelial infiltration is one of the most difficult complication to treat. Our purpose is to evaluate corneal transparency, recurrence, and visual acuity in patients with adenoviral subepithelial infiltration by first removing the infiltrative stroma with a smile and implanting the same volume of fresh lenticule in the prepared stromal pocket.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT05123014
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other Eye Hospital Pristina Kosovo trials
Trials by the same sponsor.
- NCT04642729 — Fresh Corneal Lenticule Implantation in Macular Corneal Distrophy With Relex Smile Surgery · NA · unknown
- NCT04594512 — Fresh Corneal Lenticule Implantation and Autologous Serum - Case Report · NA · active not recruiting
- NCT04616144 — Fresh Corneal Lenticule Implantation in Hyperopic Patients With High Astigmatism · NA · active not recruiting
- NCT04793893 — Treatment of Residual Hypermetropic Refraction on Young Patients After LASIK Using Human Fresh Corneal Lenticule Implant · NA · unknown
- NCT04468022 — Toric Trifocal IOL Treatment With High Astigmatism and Hyperopia vs SMILE Enhancement After Trifocal IOL Treatment · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05123014 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Eye Hospital Pristina Kosovo
- Last refreshed: 25 February 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05123014.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing