NCT05122988 (FACE) is a clinical trial in Adverse Childhood Experiences, sponsored by University of Applied Sciences and Arts Northwestern Switzerland.

Who is sponsoring NCT05122988?

NCT05122988 is sponsored by University of Applied Sciences and Arts Northwestern Switzerland.

What condition does NCT05122988 study?

NCT05122988 studies Adverse Childhood Experiences.

Is NCT05122988 still recruiting?

NCT05122988 is currently completed. Last updated 24 December 2025.

Last reviewed 2025-12-24 · How we verify

NCT05122988: FACE

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Facing Adverse Childhood Experiences

Completed Last updated 24 December 2025

What this trial tests

trial in Adverse Childhood Experiences in 2,606 participants. Completed in 1 May 2024.

Timeline

28 October 2021

Primary endpoint
1 May 2024

1 May 2024

Quick facts

Lead sponsor	University of Applied Sciences and Arts Northwestern Switzerland
Status	Completed
Study type	OBSERVATIONAL
Enrollment	2,606
Start date	28 October 2021
Primary completion	1 May 2024
Estimated completion	1 May 2024
Sites	1 location across Switzerland

Conditions studied

Adverse Childhood Experiences — all drugs for Adverse Childhood Experiences →

Sponsor

University of Applied Sciences and Arts Northwestern Switzerland

Who can join

Adults 18 to 21, any sex, with Adverse Childhood Experiences. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Childhood experiences affect psychosocial well-being and mental health across the life course for better or worse. The aim of the present study is to investigate how adverse childhood experiences before the age of 18 impact psychological functioning in young adulthood, and whether social information processing and emotion regulation may mediate these associations.

Publications & conference data

3 peer-reviewed publications reference this trial (live from Europe PMC):

Investigating emotion regulation and social information processing as mechanisms linking adverse childhood experiences with psychosocial functioning in young swiss adults: the FACE epidemiological accelerated cohort study.
Brodbeck J, Bötschi SIR, Vetsch N, Berger T, et al · · 2022 · cited 10× · PMID 35410310 · DOI 10.1186/s40359-022-00798-5
Perseverative thinking, threat interpretation bias, and emotional reactivity as mediators between adverse childhood experience domains and psychopathology: A longitudinal mediation study in a cohort of Swiss emerging adults.
Brodbeck J, Jacinto S, Stallmann L, Vetsch N, et al · · 2025 · cited 1× · PMID 41488809 · DOI 10.1016/j.ijchp.2025.100654
Exposure frequencies of single adverse childhood experiences and their association with psychological distress: evidence from a cohort study among emerging Swiss adults.
Marmet S, Bötschi SIR, Vetsch N, Stallmann L, et al · · 2025 · cited 1× · PMID 41437003 · DOI 10.1186/s12889-025-25999-6

Verify or expand the search:

Other recruiting trials for Adverse Childhood Experiences

Currently open trials in the same condition.

NCT05377372 — Early Life Exposures Among Children With Sickle Cell Disease · NA · recruiting
NCT06821035 — The THRIVE Study: Teaching Healthy Regulation in Individuals & Vulnerable Environments · NA · recruiting
NCT07073352 — ACEs, SIRT1, and Premature Vascular Aging in Humans · NA · recruiting
NCT06619821 — Effects of Parent-Adolescent Joint Interventions for Adolescents With Adverse Childhood Experiences · NA · active not recruiting
NCT06454344 — The Iowa ACEs and Sleep Cohort and Manipulating Sleep in Young Adults With ACEs Studies · NA · recruiting

Other University of Applied Sciences and Arts Northwestern Switzerland trials

Trials by the same sponsor.

NCT03519815 — Clinical Study to Evaluate the Efficacy of Ectoin® Containing Eye Spray for Treatment of Dry Eye Disease · NA · completed
NCT04637516 — Evaluation of an Updated Version of the Program "BlinkBlink" for Alleviation of Dry Eye Symptoms Induced by Computer Wor · NA · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05122988 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University of Applied Sciences and Arts Northwestern Switzerland
Last refreshed: 24 December 2025

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05122988.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing