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NCT05122481: VITA-C4CARE

Vitamin C 4 Care Homes

Status unknown NA Last updated 18 May 2022
What this trial tests

NA trial testing Vitamin C in Hypovitaminosis in 20 participants. Status unknown.

Timeline
15 January 2023
Primary endpoint
30 July 2023
30 July 2023

Quick facts

Lead sponsorUniversity of Aberdeen
PhaseNA
StatusStatus unknown
Study typeINTERVENTIONAL
Allocationna
Designsingle group
Maskingnone
Primary purposeother
Enrollment20
Start date15 January 2023
Primary completion30 July 2023
Estimated completion30 July 2023
Sites1 location across United Kingdom

Drugs / interventions tested

Conditions studied

Sponsor

University of Aberdeen

Who can join

Adults 65 to 100, any sex, with Hypovitaminosis or Vitamin C Abnormal. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Older people in care homes are one of the most vulnerable groups with respect to risk, morbidity and mortality of severe coronavirus disease-2019 (COVID-19). In the UK, almost half (47%) of all COVID-19 deaths occurred in care homes. The World Health Organization (WHO) has highlighted vitamin C as an adjunctive therapy with biological plausibility for people with severe COVID-19. Previous research has indicated that up to 40% of care home residents in the UK are deficient in vitamin C, an essential immune supportive nutrient. This is a 10-fold higher deficiency level than that reported in community dwelling older people in the UK government's National Diet and Nutrition Survey. Due to lack of robust pharmacokinetic data in older people, the intake required to optimise the vitamin C status of this cohort is not yet known and may be higher than that for healthy adults; some have estimated as high as 400 mg/d (the current UK recommended nutrient intake (RNI) or vitamin C is 40 mg/d, which is sufficient to prevent deficiency, but not enough for optimal/saturating vitamin C status). Thus, this pilot and feasibility study will assess the intake requirements of care home residents for optimal vitamin C status. The purpose is to provide essential data for a future clinical trial assessing the efficacy of optimal vitamin C supplementation for risk, severity, and duration of respiratory infections in this population who are at risk of such infections.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

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Other trials of Vitamin C

Trials testing the same drug.

Other University of Aberdeen trials

Trials by the same sponsor.

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Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05122481.

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