NCT05121220 (orthoretenti) is a NA clinical trial of fixed retainer in Orthodontic Relapse, sponsored by Poliklinika Orthonova.

Who is sponsoring NCT05121220?

NCT05121220 is sponsored by Poliklinika Orthonova.

What drugs are being tested in NCT05121220?

Interventions in NCT05121220: fixed retainer, removable retainer.

What condition does NCT05121220 study?

NCT05121220 studies Orthodontic Relapse.

Is NCT05121220 still recruiting?

NCT05121220 is currently status unknown. Last updated 9 May 2022.

Last reviewed 2022-05-09 · How we verify

NCT05121220: orthoretenti

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Efficacy and Cost-effectiveness of Orthodontic Retention Protocols

Status unknown NA Last updated 9 May 2022

What this trial tests

NA trial testing fixed retainer in Orthodontic Relapse in 152 participants. Status unknown.

Timeline

15 November 2020

Primary endpoint
15 November 2022

15 November 2023

Quick facts

Lead sponsor	Poliklinika Orthonova
Phase	NA
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	prevention
Enrollment	152
Start date	15 November 2020
Primary completion	15 November 2022
Estimated completion	15 November 2023
Sites	1 location across Croatia

Drugs / interventions tested

fixed retainer
removable retainer

Conditions studied

Orthodontic Relapse — all drugs for Orthodontic Relapse →

Sponsor

Poliklinika Orthonova

Who can join

Adults 11 to 18, any sex, with Orthodontic Relapse. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Objective is to assess changes of dentition and periodontium, and hygiene in retention after the end of the active phase of orthodontic treatment, and relationship with gender, type of retention appliance, pre-therapeutic condition of dentition and duration of active phase of treatment.

Publications & conference data

3 peer-reviewed publications reference this trial (live from Europe PMC):

Retention procedures for stabilising tooth position after treatment with orthodontic braces.
Martin C, Littlewood SJ, Millett DT, Doubleday B, et al · · 2023 · cited 20× · PMID 37219527 · DOI 10.1002/14651858.cd002283.pub5
Stability, survival and costs of vacuum-formed retainers versus bonded lingual braided rectangular and multistranded round wire retainers in the mandible of orthodontic patients over a two-year period.
Kanizaj Ugrin S, Kiseri Kubati J, Cirgic E, Simeon P, et al · · 2025 · PMID 41239352 · DOI 10.1186/s12903-025-07174-w
Comparison of efficacy of thermoplastic retainer with round and rectangular bonded lingual wire retainer in the mandible two years after orthodontic treatment: a randomised controlled trial.
Kanizaj Ugrin S, Špalj S. · · 2024 · PMID 38424224 · DOI 10.1007/s00784-024-05572-y

Verify or expand the search:

Other recruiting trials for Orthodontic Relapse

Currently open trials in the same condition.

NCT05006339 — The Use of Remote Monitoring for Orthodontic Retention Review · NA · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05121220 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Poliklinika Orthonova
Last refreshed: 9 May 2022

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05121220.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing