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NCT05120180: PLEDGE-Surgery
Effect of ALND With Vein Branches Reservation on Postoperative Upper Limb Edema and Dysfunction in Breast Cancer
NA trial testing axillary lymph node dissection with vein branches reservation in Breast Cancer Lymphedema in 258 participants. Participants enrolled and being followed up; not accepting new ones.
1 April 2024
Quick facts
| Lead sponsor | Xiangyun Zong |
|---|---|
| Phase | NA |
| Status | Active, enrolled |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | triple |
| Primary purpose | treatment |
| Enrollment | 258 |
| Start date | 3 January 2022 |
| Primary completion | 1 April 2024 |
| Estimated completion | 1 April 2029 |
| Sites | 3 locations across China |
Drugs / interventions tested
- axillary lymph node dissection with vein branches reservation
- axillary lymph node dissection without vein branches reservation
Conditions studied
- Breast Cancer Lymphedema — all drugs for Breast Cancer Lymphedema →
Sponsor
Xiangyun Zong
Who can join
Adults 18 to 69, any sex, with Breast Cancer Lymphedema. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The purpose of this study is to compare the effects of axillary lymph node dissection with or without axillary vein branches reservation on the affected upper limb edema and dysfunction in breast cancer patients, and to explore the solutions to prevent the affected upper limb edema and dysfunction after ALND.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT05120180
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Breast Cancer Lymphedema
Currently open trials in the same condition.
- NCT07420725 — The Relationship Between Gait Parameters and Balance Disorder and Fall Risk in Breast Cancer-Related Lymphedema(BCRL) · active not recruiting
- NCT06302361 — Lymphovenous Anastomosis for Breast Cancer Lymphedema · NA · active not recruiting
- NCT05725265 — LLLT for BCRL: a Randomized, Placebo-controlled Study · NA · recruiting
- NCT05983380 — The Effect of Hand Exercises on Upper Limb Volume, Quality of Life, and Hand Function in Breast Cancer Survivors · NA · recruiting
- NCT05441943 — Lymphaticovenous Anastomosis as Treatment for Lymphedema · NA · active not recruiting
Other Xiangyun Zong trials
Trials by the same sponsor.
- NCT04789889 — Comparison Between IORT and Postoperative Radiotherapy in Breast Conserving Surgery · NA · terminated
- NCT02518191 — Effects of GnRHa on Ovarian Function Against Chemotherapy-induced-gonadotoxicity · Phase 3 · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05120180 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Xiangyun Zong
- Last refreshed: 19 September 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05120180.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing