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NCT05120141
A Twelve Week Study of Experimental Mouth Rinses
Phase 4 trial testing Colgate Cavity Protection Toothpaste in Gingivitis in 300 participants. Completed in 23 July 2021.
23 July 2021
Quick facts
| Lead sponsor | Johnson & Johnson Consumer Inc. (J&JCI) |
|---|---|
| Phase | Phase 4 |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | other |
| Enrollment | 300 |
| Start date | 29 March 2021 |
| Primary completion | 23 July 2021 |
| Estimated completion | 23 July 2021 |
| Sites | 1 location across Canada |
Drugs / interventions tested
- Colgate Cavity Protection Toothpaste — full drug profile →
- American Dental Association (ADA) Ref Toothbrush
- Prototype 1 Mouth Rinse
- Prototype 2 Mouth Rinse
- Prototype 3 Mouth Rinse
- Listerine Cool Mint Mouth Rinse
- Hydroalcohol Mouth Rinse
Conditions studied
- Gingivitis — all drugs for Gingivitis →
- Plaque — all drugs for Plaque →
Sponsor
Johnson & Johnson Consumer Inc. (J&JCI) — full company profile →
Who can join
Adults 18 to 60, any sex, with Gingivitis or Plaque. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The purpose of this study is to evaluate the safety and efficacy of experimental mouth rinse formulations compared to a hydroalcohol control mouth rinse and a positive control mouth rinse for the reduction of gingivitis and plaque when used as an adjunct to tooth brushing during a twelve-week product usage period.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT05120141
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Colgate Cavity Protection Toothpaste
Trials testing the same drug.
- NCT07169188 — A Clinical Study Investigating the Efficacy of an Experimental Toothpaste Containing Stannous Fluoride in Improving Ging · NA · completed
- NCT07257042 — Oothpaste Containing 8% Arginine Compared to Colgate Cavity Protection Toothpaste in Reducing Dentinal Hypersensitivity · Phase 3 · completed
- NCT06602466 — A Clinical Study Investigating the Effect of an Experimental Toothpaste Containing Stannous Fluoride in Improving Gingiv · NA · completed
- NCT06427499 — The Clinical of Stannous Fluoride Toothpaste and a Newly Designed Toothbrush Compared to Colgate Cavity Protection Tooth · Phase 3 · completed
- NCT06136455 — A Study to Investigate Salivary Flow and Potential of Hydrogen (pH) Following Use of Essential-Oil Containing Mouthwashe · Phase 4 · completed
Other recruiting trials for Gingivitis
Currently open trials in the same condition.
- NCT07501455 — Comparison of the Effects of Oral Hygiene Regimens on Clinical, Immunomodulatory, and Microbial Outcomes and Oral Tolera · NA · recruiting
- NCT07499596 — Effect of Morus Nigra Mouthwash on Gingivitis Treatment · NA · recruiting
- NCT07270705 — Assessment of the Efficacy and Safety of OROXID® Oral Solution in Patients With Gingivitis · NA · recruiting
- NCT07164989 — Motivational Interviewing to Improve Oral Hygiene in Adolescent Orthodontic Patients · NA · active not recruiting
- NCT07530978 — ORAL HYGIENE, PERIODONTAL STATUS AND QUALITY OF LIFE · recruiting
Other Johnson & Johnson Consumer Inc. (J&JCI) trials
Trials by the same sponsor.
- NCT06852742 — A Study to Evaluate and Compare the Efficacy of Two Facial Creams on Moderately to Severely Photodamaged Skin · NA · completed
- NCT06734299 — A Study to Evaluate Usage of Mineral Sunscreens With Differentiated Whitening Attributes in Multi-Cultural Skin Tones · NA · completed
- NCT06658847 — A Study to Evaluate the Effect of a Topical Retinol on Epigenetic Changes and Expression of Certain Genes in the Skin Us · NA · completed
- NCT06654102 — A Study to Evaluate the Cutaneous Effects of Deep Ultraviolet A +/- High-Energy Visible Blue Light Exposure · NA · completed
- NCT06318637 — Evaluation of the Acceptability and Feasibility of a Bedtime Routine for Neonates · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05120141 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Johnson & Johnson Consumer Inc. (J&JCI)
- Last refreshed: 29 June 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05120141.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing