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NCT05118672: RESFRIN
Phase 3 Clinical Trial to Evaluate Paracetamol /Fexofenadine /Phenylephrine in Flu and Cold Treatment
Phase 3 trial testing Experimental drug (paracetamol 500mg / fexofenadine 60mg / phenylephrine 20mg) in Cold in 567 participants. Completed in 26 August 2025.
26 August 2025
Quick facts
| Lead sponsor | Eurofarma Laboratorios S.A. |
|---|---|
| Phase | Phase 3 |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | treatment |
| Enrollment | 567 |
| Start date | 26 March 2025 |
| Primary completion | 26 August 2025 |
| Estimated completion | 26 August 2025 |
| Sites | 2 locations across Brazil |
Drugs / interventions tested
- Experimental drug (paracetamol 500mg / fexofenadine 60mg / phenylephrine 20mg) — full drug profile →
- Placebo
Conditions studied
- Cold — all drugs for Cold →
- Flu Symptom — all drugs for Flu Symptom →
Sponsor
Eurofarma Laboratorios S.A. — full company profile →
Who can join
18 and older, any sex, with Cold or Flu Symptom. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
A Phase 3, multicenter, Randomized, Double-blind, comparative clinical trial to evaluate the association of paracetamol 500mg + Fexofenadine 60mg + Phenylephrine 20mg in the flu and common cold treatment. ⚠️Study will only be conducted in research centers in Brazil (please do not send e-mail if your center is outside brazil).
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT05118672
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Cold
Currently open trials in the same condition.
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Other Eurofarma Laboratorios S.A. trials
Trials by the same sponsor.
- NCT07529977 — Phase 3 Study to Evaluate the Efficacy and Safety of Oral Minoxidil (N1087) in Men With Androgenetic Alopecia. · Phase 3 · not yet recruiting
- NCT06560333 — iSGLT2 Inhibitor and a iDPP -4 Inhibitor in Treatment of Type 2 Diabetes Mellitus in Patients Treated With Metformin (TR · Phase 3 · withdrawn
- NCT06546735 — Efficacy and Safety of Two Fixed-dose Combinations in Men with Lower Urinary Tract Symptoms Associated with Benign Prost · Phase 3 · not yet recruiting
- NCT06608472 — Fixed-dose Combination of an Angiotensin Receptor Blocker and Thiazide Diuretic for Essential Hypertension · Phase 3 · not yet recruiting
- NCT05683574 — Fixed-dose Combination of Etoricoxib + Cyclobenzaprine for Pain Relief After Third Molar Extraction in Brazil · Phase 3 · withdrawn
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05118672 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Eurofarma Laboratorios S.A.
- Last refreshed: 22 September 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05118672.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing