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Simplified Bowel Preparation Versus Standard Bowel Preparation Before Capsule Endoscopy in Patients With Crohn's Disease (CROHN-PREP)
The European guidelines currently recommend to use 2 L of polyethylene glycol and free residue diet before any capsule endoscopy. However, up to now, no studies have been conducted to specifically evaluate bowel preparation modalities before small bowel capsule endoscopy in patients with Crohn's disease. In patients with Crohn's disease and small bowel ulcers, polyethylene glycol may remove some fibrin from these ulcers and alter bowel preparation. Moreover, it is important to select the most acceptable bowel preparation because patients with Crohn's disease will have to repeat capsule endoscopy several times after initiating treatment, for monitoring under treatment, or for detection of post-operative recurrence. In a preliminary retrospective study, it has been suggested that a simplified bowel preparation with liquid diet the evening before and water on the morning of the capsule endoscopy induced a better bowel preparation than the standard method with polyethylene glycol. Thus, the aim of the study is to demonstrate the superiority of this simplified bowel preparation compared to the standard preparation modality in terms of quality of bowel preparation, patient's acceptability and diagnostic yield.
Details
| Lead sponsor | Nantes University Hospital |
|---|---|
| Phase | NA |
| Status | COMPLETED |
| Enrolment | 144 |
| Start date | Tue Jul 05 2022 00:00:00 GMT+0000 (Coordinated Universal Time) |
| Completion | Mon Apr 22 2024 00:00:00 GMT+0000 (Coordinated Universal Time) |
Conditions
- Crohn Disease
Interventions
- capsule endoscopy
- standard small bowel preparation
- Simplified small bowel preparation
Countries
France