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NCT05117034
Pre-emptive Intravenous Morphine for Acute Post-craniotomy Pain.
NA trial testing Morphine in Pain, Postoperative in 115 participants. Participants enrolled and being followed up; not accepting new ones.
1 May 2025
Quick facts
| Lead sponsor | Tel-Aviv Sourasky Medical Center |
|---|---|
| Phase | NA |
| Status | Active, enrolled |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | quadruple |
| Primary purpose | treatment |
| Enrollment | 115 |
| Start date | 16 February 2022 |
| Primary completion | 1 May 2025 |
| Estimated completion | 1 May 2025 |
| Sites | 1 location across Israel |
Drugs / interventions tested
- Morphine
- Nacl 0.9%
Conditions studied
- Pain, Postoperative — all drugs for Pain, Postoperative →
- Anesthesia — all drugs for Anesthesia →
- Analgesia — all drugs for Analgesia →
Sponsor
Tel-Aviv Sourasky Medical Center
Who can join
Adults 18 to 80, any sex, with Pain, Postoperative or Anesthesia. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
We propose a double-blind randomized controlled trial to evaluate the effect of intravenously administered morphine at surgery conclusion on acute postoperative pain in patients recovering from craniotomy surgery. Participating adults having craniotomy surgery will be randomized in a 1:1 ratio to intraoperative intravenous administration of 0.08 mg/kg morphine at dura closure, or a matching placebo.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT05117034
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05117034 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Tel-Aviv Sourasky Medical Center
- Last refreshed: 20 November 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05117034.
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